Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487643 | 0.92 | ACHE (0.90) | ACHEBCHE | |
| SCHEMBL5485655 | 0.91 | ACHE (0.97) | ACHEBCHE | |
| SCHEMBL5945380 | 0.90 | ACHE (1.00) | ACHEBCHE | |
| SCHEMBL5486217 | 0.90 | ACHE (1.00) | ACHEBCHE | |
| SCHEMBL5945371 | 0.90 | ACHE (1.00) | ACHEBCHE | |
| SCHEMBL5489233 | 0.90 | ACHE (1.00) | ACHEBCHE | |
| SCHEMBL1537859 | 0.90 | ACHE (1.00) | ACHEBCHE | |
| SCHEMBL24000133 | 0.89 | BCHE (0.97) | ACHEBCHE | |
| SCHEMBL13480729 | 0.89 | BCHE (0.92) | ACHEBCHE | |
| SCHEMBL15168191 | 0.87 | ACHE (1.00) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116375684-B | AChE-EGFR double-target inhibitor and preparation method and application thereof | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-116375684-A | AChE-EGFR double-target inhibitor and preparation method and application thereof | 中国药科大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-111592530-B | Acldoxime-containing tacrine derivative selective butyrylcholinesterase inhibitor and preparation method and application thereof | 山东大学 | 2021-09-24 | — | — | CN | disclosed |
| WO-2021047572-A1 | GSK-3β/CHE DOUBLE INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国药科大学 | 2021-03-18 | — | — | WO | disclosed |
| CN-111349085-B | Pyrimidone compounds or pharmaceutically acceptable salts thereof, preparation method and application | 中国药科大学 | 2021-02-09 | — | — | CN | disclosed |
| CN-111592530-A | Acldoxime-containing tacrine derivative selective butyrylcholinesterase inhibitor and preparation method and application thereof | 山东大学 | 2020-08-28 | — | — | CN | disclosed |
| CN-111349085-A | Pyrimidone compounds or pharmaceutically acceptable salts thereof, preparation method and application | 中国药科大学 | 2020-06-30 | — | — | CN | disclosed |
| US-10557853-B2 | Molecular sensor and methods of use thereof | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2020-02-11 | — | — | US | disclosed |
| US-20170307625-A1 | MOLECULAR SENSOR AND METHODS OF USE THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2017-10-26 | — | — | US | disclosed |
| US-9696310-B2 | Molecular sensor and methods of use thereof | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2017-07-04 | — | — | US | disclosed |
| US-20150276753-A1 | MOLECULAR SENSOR AND METHODS OF USE THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2015-10-01 | — | — | US | disclosed |
| US-20070299093-A1 | Organic Compounds Useful for the Treatment of Alzheimer's Disease, Their Use and Method of Preparation | Alma Mater Studiorum-Universitá Di Bologna (IT) | 2007-12-27 | — | — | US | disclosed |
| US-7307083-B2 | Tetrahydro-acridine and dithiolane derivatives | ALMA MATER STUDIORUM-UNIVERSITA'DI BOLOGNA (IT) | 2007-12-11 | — | — | US | disclosed |
| US-20070219241-A1 | Organic Compounds Useful For The Treatment Of Alzheimer's Disease, Their Use And Method Of Preparation | ALMA MATER STUDIORUM-UNIVERSITA'DI BOLOGNA (IT) | 2007-09-20 | — | — | US | disclosed |
| US-4608383-A | Cardioactive pyrazole and imidazole aryloxypropanolamines | BOEHRINGER MANNHEIM GMBH (DE) | 1986-08-26 | — | — | US | disclosed |
| US-4438128-A | ADRENERGIC BLOCKERS | BOEHRINGER MANNHEIM GMBH (DE) | 1984-03-20 | — | — | US | disclosed |
| EP-0042593-A1 | Aryloxy-propanol amines, process for their preparation and medicines containing these compounds | Roche Diagnostics GmbH (DE) | 1981-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219241-A1 | Organic Compounds Useful For The Treatment Of Alzheimer's Disease, Their Use And Method Of Preparation | OTC, PSEN2, PSEN1 | ACHE 5/4885BCHE 7/4885 |
| US-20150276753-A1 | MOLECULAR SENSOR AND METHODS OF USE THEREOF | MAVS, STIM1, HSPE1 | ACHE 4544/4885BCHE 4659/4885 |
| US-20170307625-A1 | MOLECULAR SENSOR AND METHODS OF USE THEREOF | MAVS, STIM1, HSPE1 | ACHE 4544/4885BCHE 4659/4885 |
| US-20070299093-A1 | Organic Compounds Useful for the Treatment of Alzheimer's Disease, Their Use and Method of Preparation | OTC, PSEN2, PSEN1 | ACHE 5/4885BCHE 7/4885 |
| US-10557853-B2 | Molecular sensor and methods of use thereof | MAVS, STIM1, HSPE1 | ACHE 4544/4885BCHE 4659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.