Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5480578 | 0.85 | POLB (0.53) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL5480579 | 0.85 | POLB (0.53) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL5487804 | 0.85 | GPR27 (0.54) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL5487810 | 0.85 | GPR27 (0.54) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL5489320 | 0.85 | GPR27 (0.60) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL5489322 | 0.85 | GPR27 (0.60) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL5482273 | 0.84 | GPR27 (0.48) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL5489429 | 0.79 | IKBKB (0.60) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL5487532 | 0.79 | KMT2A (0.62) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL5489426 | 0.79 | IKBKB (0.60) | MEN1KMT2AALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845083-A2 | New arylsulfonohydrazide inhibitors of enzymes MurC and MurD | UNIVERZA V LJUBLJANI, FAKULTETA ZA FARMACIJO (SI) | 2007-10-17 | — | — | EP | disclosed |