Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.44 |
| ▸ | MMP14 | P50281 | 9/20 | 0.44 |
| ▸ | MMP12 | P39900 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL587505 | 1.00 | MMP13 (0.44) | MMP13MMP14MMP12 | |
| SCHEMBL587427 | 0.97 | MMP13 (0.43) | MMP13MMP14MMP12 | |
| SCHEMBL3109399 | 0.96 | MMP13 (0.42) | MMP13MMP14MMP12 | |
| SCHEMBL588084 | 0.88 | MMP13 (0.34) | MMP13MMP14MMP12 | |
| SCHEMBL585311 | 0.88 | MMP13 (0.34) | MMP13MMP14MMP12 | |
| SCHEMBL5492410 | 0.88 | MMP13 (0.42) | MMP13MMP14MMP12 | |
| SCHEMBL587491 | 0.88 | ADAMTS5 (0.35) | MMP13MMP14MMP12 | |
| SCHEMBL587143 | 0.88 | MMP13 (0.42) | MMP13MMP14MMP12 | |
| SCHEMBL587210 | 0.88 | MMP13 (0.41) | MMP13MMP14MMP12 | |
| SCHEMBL5318545 | 0.86 | MMP13 (0.45) | MMP13MMP14MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831199-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2007-09-12 | — | — | EP | claimed |
| WO-2006065215-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2006-06-22 | — | — | WO | claimed |