Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1740136 | 0.77 | ALDH1A1 (0.35) | ALDH1A1POLBKMT2AMEN1TSHR | |
| SCHEMBL1738448 | 0.76 | ALDH1A1 (0.34) | ALDH1A1POLBKMT2AMEN1TSHR | |
| SCHEMBL1738792 | 0.74 | ALDH1A1 (0.37) | ALDH1A1POLBKMT2AMEN1TSHR | |
| SCHEMBL1401611 | 0.71 | KMT2A (0.47) | POLBKMT2AFABP5EPHX2 | |
| SCHEMBL29996541 | 0.71 | KMT2A (0.47) | POLBKMT2AFABP5EPHX2 | |
| SCHEMBL60475 | 0.70 | FABP5 (0.45) | ALDH1A1KMT2AMEN1TSHRGPR55 | |
| SCHEMBL29400602 | 0.70 | FABP5 (0.39) | TAS1R3TAS1R1ALDH1A1POLBKMT2A | |
| SCHEMBL1740093 | 0.69 | FABP5 (0.38) | TAS1R3TAS1R1ALDH1A1POLBKMT2A | |
| SCHEMBL1739364 | 0.68 | ALDH1A1 (0.38) | TAS1R3TAS1R1ALDH1A1POLBKMT2A | |
| SCHEMBL1737775 | 0.67 | ALDH1A1 (0.38) | ALDH1A1POLBKMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858538-A2 | MUCIN HYPERSECRETION INHIBITORS BASED ON THE STRUCTURE OF MANS AND METHODS OF USE | Biomarck Pharmaceuticals, Ltd. (US) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006078899-A2 | MUCIN HYPERSECRETION INHIBITORS BASED ON THE STRUCTURE OF MANS AND METHODS OF USE | BIOMARCK PHARMACEUTICALS, LTD. (US) | 2006-07-27 | — | — | WO | disclosed |