SCHEMBL1401611

SCHEMBL1401611

O=C(OCC1c2ccccc2-c2ccccc21)Oc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.47
▸ FABP5 Q01469 3/20 0.46
▸ FABP7 O15540 2/20 0.46
▸ EPHX2 P34913 1/20 0.44
▸ CA1 P00915 1/20 0.42
▸ CA2 P00918 1/20 0.42
▸ CASP3 P42574 1/20 0.40
▸ POLB P06746 1/20 0.38
▸ DPP8 Q6V1X1 1/20 0.37
▸ DPP9 Q86TI2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29996541 1.00 KMT2A (0.47) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL44676 0.82 KMT2A (0.58) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL31072600 0.82 KMT2A (0.40) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL31733654 0.80 KMT2A (0.51) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL29400520 0.80 KMT2A (0.51) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL3060297 0.80 KMT2A (0.51) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL27143076 0.80 FABP5 (0.52) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL15119354 0.80 KMT2A (0.60) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL29401144 0.79 CASP3 (0.48) KMT2AEPHX2CASP3
SCHEMBL7650015 0.79 CASP3 (0.48) KMT2AEPHX2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115181249-A Electron-withdrawing group functionalized hypercrosslinked polymer and preparation method and application thereof 中南民族大学 2022-10-14 — — CN claimed
EP-1498978-B1 NONAQUEOUS ELECTROLYTIC SOLUTION AND LITHIUM SECONDARY BATTERY EMPLOYING THE SAME UBE INDUSTRIES (JP) 2010-09-08 — — EP claimed
US-7297442-B2 Nonaqueous electrolytic solution and lithium secondary battery employing the same UBE INDUSTRIES, LTD. (JP) 2007-11-20 — — US claimed
US-20050255384-A1 Nonaqueous electrolytic solution and lithium secondary battery employing the same UBE INDUSTRIES, LTD (JP) 2005-11-17 — — US claimed
EP-1498978-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND LITHIUM SECONDARY BATTERY EMPLOYING THE SAME Ube Industries, Ltd. (JP) 2005-01-19 — — EP claimed
US-5098999-A Amidation of amino acids like dopa for use as adhesives and for treatment of Parkinson*s disease HITACHI CHEMICAL COMPANY (JP) 1992-03-24 — — US claimed
CN-115181249-A Electron-withdrawing group functionalized hypercrosslinked polymer and preparation method and application thereof 中南民族大学 2022-10-14 — — CN disclosed
EP-3052134-B1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES MERCK SHARP & DOHME (US) 2021-05-05 — — EP disclosed
EP-3782220-A1 AN ELECTROLYTE COMPOSITION FOR A LITHIUM-ION BATTERY AND A LITHIUM-ION BATTERY Karlsruher Institut für Technologie (DE) 2021-02-24 — — EP disclosed
CN-105792852-B Glucose-responsive insulin conjugates 默沙东公司 2019-12-10 — — CN disclosed
US-9889205-B2 Glucose-responsive insulin conjugates MERCK SHARP & DOHME CORP. (US) 2018-02-13 — — US disclosed
US-9884125-B2 Glucose-responsive insulin conjugates MERCK SHARP & DOHME CORP. (US) 2018-02-06 — — US disclosed
US-20160303244-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES MERCK SHARP & DOHME CORP. (US) 2016-10-20 — — US disclosed
US-5965524-A BIOSURFACTANTS, ANTIBACTERIAL, ANTIVIRAL AND ANTITRYPANOSOMAL THERAPEUTIC COMPOUNDS PEPTIDE TECHNOLOGIES CORPORATION (US) 1999-10-12 — — US disclosed
EP-0400972-B1 Fluorescent degree of cure monitors MINNESOTA MINING & MFG (US) 1996-07-03 — — EP disclosed
US-5182316-A Forming a UV-detectable fluorophore in a mixture of hydride containing silicone, unsaturated silicone, cationically sensitive compound and a latent dibenzofulvene MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-01-26 — — US disclosed
US-5118559-A Dibenzofulvene compound MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-06-02 — — US disclosed
US-5098999-A Amidation of amino acids like dopa for use as adhesives and for treatment of Parkinson*s disease HITACHI CHEMICAL COMPANY (JP) 1992-03-24 — — US disclosed
US-5047444-A Hydrosilatable polysiloxanes, unsaturated compounds and a dibenzofulvene chromogen; coatings MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-09-10 — — US disclosed
EP-0400972-A2 Fluorescent degree of cure monitors MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-12-05 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160303244-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES GPR119, INSR, IRS1 KMT2A 2821/4885FABP5 1792/4885FABP7 434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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