Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 12/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3647163 | 0.87 | FFAR2 (0.37) | LOXL2FFAR2HCAR2NPSR1NCOA1 | |
| Hydrochloric Acid SCHEMBL2405970 | 0.85 | FFAR2 (0.36) | LOXL2FFAR2HCAR2NPSR1NCOA1 | |
| SCHEMBL11730112 | 0.84 | NPSR1 (0.41) | FFAR2HCAR2NPSR1NCOA1NCOA3 | |
| SCHEMBL11709354 | 0.84 | FFAR2 (0.39) | FFAR2HCAR2NPSR1NCOA1NCOA3 | |
| SCHEMBL5911684 | 0.83 | CDC7 (0.55) | LOXL2HPGDALDH1A1GAACDC7 | |
| SCHEMBL16761206 | 0.83 | FFAR2 (0.39) | FFAR2HCAR2NPSR1NCOA1NCOA3 | |
| SCHEMBL5495944 | 0.82 | HCAR2 (0.52) | LOXL2HCAR2LOXKDM4EALDH1A1 | |
| SCHEMBL5887745 | 0.81 | NPSR1 (0.40) | FFAR2HCAR2NPSR1NCOA1NCOA3 | |
| SCHEMBL2075036 | 0.80 | HDAC6 (0.39) | FFAR2HCAR2NPSR1NCOA1NCOA3 | |
| SCHEMBL13447371 | 0.79 | TSHR (0.41) | FFAR2NPSR1LMNAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113943263-B | Synthesis method of 2- (aminomethyl) -1, 3-thiazole-5-carboxylic acid methyl ester | 凯美克(上海)医药科技有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-113943263-B | Synthesis method of 2- (aminomethyl) -1, 3-thiazole-5-carboxylic acid methyl ester | 凯美克(上海)医药科技有限公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-113943263-B | Synthesis method of 2- (aminomethyl) -1, 3-thiazole-5-carboxylic acid methyl ester | 凯美克(上海)医药科技有限公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-113943263-B | Synthesis method of 2- (aminomethyl) -1, 3-thiazole-5-carboxylic acid methyl ester | 凯美克(上海)医药科技有限公司 | 2025-03-21 | — | — | CN | disclosed |
| US-7169759-B1 | Tetrapeptide inhibitors of β-secretase | ELAN PHARMACEUTICALS, INC. (US) | 2007-01-30 | — | — | US | disclosed |
| EP-1192177-A1 | STATINE-DERIVED TETRAPEPTIDE INHIBITORS OF BETA-SECRETASE | Elan Pharmaceuticals, Inc. (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000077030-A1 | STATINE-DERIVED TETRAPEPTIDE INHIBITORS OF BETA-SECRETASE | ELAN PHARMACEUTICALS, INC. (US) | 2000-12-21 | — | — | WO | disclosed |