SCHEMBL5493318

SCHEMBL5493318

Clc1ccc(Cl)c(CCC[Si](Cl)(Cl)Cl)c1Cl

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.32
GAA P10253 1/20 0.31
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5487912 0.94 AR (0.31) ARGAA
SCHEMBL1005099 0.74 TAAR1 (0.32) ARTAAR1
SCHEMBL4450247 0.74
SCHEMBL5488906 0.73 AR (0.35) ARTAAR1
SCHEMBL1800783 0.70 KDM4E (0.36) GAA
SCHEMBL17552720 0.69 TAAR1 (0.34) ARTAAR1
SCHEMBL10061023 0.69 ALDH1A1 (0.35) ARGAATAAR1
SCHEMBL6953644 0.69 TAAR1 (0.62) TAAR1
SCHEMBL10830911 0.69 TAAR1 (0.34) ARTAAR1
SCHEMBL3414586 0.69 CYP3A4 (0.39) ARGAATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7291747-B2 Silicon compounds and process for preparation thereof CHISSO CORPORATION (JP) 2007-11-06 US disclosed
US-20040143081-A1 Novel silicon compounds and process for preparation thereof JNC CORPORATION (JP) 2004-07-22 US disclosed