Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 13/20 | 0.75 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | MGLL | Q99685 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3044364 | 0.95 | HSD11B1 (0.77) | HSD11B1POLBMGLLKDM4EGAA | |
| SCHEMBL27453970 | 0.88 | MGLL (0.70) | HSD11B1MGLLALDH1A1SMN1; SMN2 | |
| SCHEMBL5492171 | 0.87 | HSD11B1 (0.69) | HSD11B1POLBMGLLKDM4EGAA | |
| SCHEMBL6236172 | 0.83 | HSD11B1 (1.00) | HSD11B1POLBMGLLKDM4EGAA | |
| SCHEMBL6212608 | 0.81 | HSD11B1 (0.74) | HSD11B1POLBMGLLKDM4EGAA | |
| SCHEMBL27943800 | 0.81 | HSD11B1 (0.74) | HSD11B1POLBMGLLKDM4EGAA | |
| SCHEMBL1720014 | 0.81 | HSD11B1 (1.00) | HSD11B1POLBMGLLKDM4EGAA | |
| SCHEMBL2556107 | 0.80 | CPB1 (0.67) | HSD11B1MGLLALDH1A1 | |
| SCHEMBL6344408 | 0.80 | HSD11B1 (0.72) | HSD11B1POLBMGLLKDM4EGAA | |
| SCHEMBL16446847 | 0.80 | KMT2A (0.77) | HSD11B1POLBMGLLCYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066259-B1 | BIOCIDAL BENZYLBIPHENYL DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2007-01-10 | — | — | EP | disclosed |
| US-6440440-B1 | BACTERICIDES, FUNGICIDES, NEMATOCIDES, MITICIDES, INSECTICIDES, AND HERBICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-08-27 | — | — | US | disclosed |
| EP-1066259-A1 | BIOCIDAL BENZYLBIPHENYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999051578-A1 | BIOCIDAL BENZYLBIPHENYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-10-14 | — | — | WO | disclosed |