SCHEMBL5493495

SCHEMBL5493495

CCO[Si](OCC)(OCC)c1ccc(C)cc1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.41
TDP1 Q9NUW8 2/20 0.37
TP53 P04637 1/20 0.37
CYP1A2 P05177 2/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
KDM4E B2RXH2 2/20 0.33
MAPT P10636 2/20 0.33
LMNA P02545 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
KMT2A Q03164 3/20 0.33
NLRP3 Q96P20 1/20 0.33
NPC1 O15118 1/20 0.33
NFKB1 P19838 1/20 0.33
RAB9A P51151 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
MEN1 O00255 2/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13027883 0.88 CYP1A2 (0.34) SMN1; SMN2TDP1CYP1A2CYP2C9CYP2C19
SCHEMBL12879282 0.86 SMN1; SMN2 (0.36) SMN1; SMN2TDP1TP53CYP1A2CYP2C9
SCHEMBL13027886 0.84 ESR1 (0.35)
SCHEMBL728384 0.82 CYP1A2 (0.32) SMN1; SMN2CYP1A2CYP2C9CYP2C19KDM4E
SCHEMBL3458211 0.82
SCHEMBL13027171 0.81 ACHE (0.48) SMN1; SMN2TDP1TP53CYP1A2CYP2C9
SCHEMBL13027134 0.81 ACHE (0.39) SMN1; SMN2TDP1CYP1A2KDM4EMAPT
SCHEMBL6652403 0.80 ALDH1A1 (0.33) CYP1A2CYP2C9CYP2C19MAPTALDH1A1
SCHEMBL8987581 0.79 CYP1A2 (0.32) SMN1; SMN2TDP1CYP1A2CYP2C9CYP2C19
SCHEMBL13027135 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4488317-A1 METHOD FOR PRODUCING CURABLE RESIN COMPOSITION Kaneka Corporation (JP) 2025-01-08 EP disclosed
CN-118556096-A Method for producing curable resin composition 株式会社钟化 2024-08-27 CN disclosed
EP-4410871-A1 POLYMER AND CURABLE COMPOSITION Kaneka Corporation (JP) 2024-08-07 EP disclosed
WO-2023162782-A1 METHOD FOR PRODUCING CURABLE RESIN COMPOSITION 株式会社カネカ 2023-08-31 WO disclosed
CN-108473684-B Process for producing siloxane polymer 东丽精细化工株式会社 2023-05-12 CN disclosed
WO-2023053988-A1 POLYMER AND CURABLE COMPOSITION 株式会社カネカ 2023-04-06 WO disclosed
US-10647821-B2 Production process for silicone polymer TORAY FINE CHEMICALS CO., LTD. (JP) 2020-05-12 US disclosed
US-20190023848-A1 PRODUCTION PROCESS FOR SILICONE POLYMER TORAY FINE CHEMICALS CO., LTD. (JP) 2019-01-24 US disclosed
US-7291747-B2 Silicon compounds and process for preparation thereof CHISSO CORPORATION (JP) 2007-11-06 US disclosed
US-20040143081-A1 Novel silicon compounds and process for preparation thereof JNC CORPORATION (JP) 2004-07-22 US disclosed
EP-0985510-B1 ARTICLE WITH UNEVEN SURFACE, PROCESS FOR PRODUCING THE SAME, AND COMPOSITION THEREFOR NIPPON SHEET GLASS CO LTD (JP) 2003-09-24 EP disclosed
US-20020064666-A1 Article having uneven surface, production process for the article, and composition for the process SHINMO KATSUHIDE (JP) 2002-05-30 US disclosed
US-6361718-B1 MOLDING POLYSILOXANE FILMS FROM SILANOLS AND SILANE HALIDES; HEAT RESISTANT AND NONCRACKING; USED TO MANUFACTURE OPTICAL RECORDING MEDIA NIPPON SHEET GLASS CO., LTD. (JP) 2002-03-26 US disclosed
EP-1142682-A1 METHOD FOR PRODUCING ARTICLE HAVING PREDETERMINED SURFACE SHAPE, AND OPTICAL WAVEGUIDE ELEMENT Nippon Sheet Glass Co., Ltd. (JP) 2001-10-10 EP disclosed
EP-0985510-A1 ARTICLE WITH ROUGH SURFACE, PROCESS FOR PRODUCING THE SAME, AND COMPOSITION THEREFOR Nippon Sheet Glass Co., Ltd. (JP) 2000-03-15 EP disclosed
EP-0258788-B1 PROCESS FOR PREPARING PROPYLENE HOMO- AND COPOLYMERS BY MEANS OF A ZIEGLER-NATTA CATALYTIC SYSTEM BASF Aktiengesellschaft (DE) 1990-05-30 EP disclosed
EP-0258788-A1 Process for preparing propylene homo- and copolymers by means of a Ziegler-Natta catalytic system BASF Aktiengesellschaft (DE) 1988-03-09 EP disclosed