Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL728325 | 0.87 | TAAR1 (0.33) | ALDH1A1POLBMAPTTAAR1 | |
| SCHEMBL729902 | 0.86 | IDO1 (0.32) | ALDH1A1IDO1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6653010 | 0.84 | TAAR1 (0.31) | ALDH1A1POLBMAPTTAAR1 | |
| SCHEMBL6653185 | 0.82 | IDO1 (0.34) | MAPTIDO1TAAR1 | |
| SCHEMBL13027769 | 0.81 | ALDH1A1 (0.32) | ALDH1A1POLBMAPTTAAR1 | |
| SCHEMBL729843 | 0.80 | TAAR1 (0.30) | TAAR1 | |
| SCHEMBL5493495 | 0.80 | SMN1; SMN2 (0.41) | ALDH1A1MAPTTAAR1CYP1A2CYP2C9 | |
| SCHEMBL13027883 | 0.80 | CYP1A2 (0.34) | ALDH1A1POLBMAPTCYP1A2CYP2C9 | |
| SCHEMBL13027724 | 0.79 | TAAR1 (0.32) | ALDH1A1POLBMAPTTAAR1 | |
| SCHEMBL730264 | 0.79 | KDM4E (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663358-A | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-02 | — | — | US | claimed |
| EP-0785206-A1 | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-07-23 | — | — | EP | claimed |
| EP-3334770-A1 | PROCESS FOR THE PREPARATION OF SILYLATED POLYMERS EMPLOYING A BACKMIXING STEP | Momentive Performance Materials Inc. (US) | 2018-06-20 | — | — | EP | disclosed |
| WO-2017027219-A1 | PROCESS FOR THE PREPARATION OF SILYLATED POLYMERS EMPLOYING A BACKMIXING STEP | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2017-02-16 | — | — | WO | disclosed |
| EP-1178077-B1 | The preparation of surface modified silica | GOODYEAR TIRE & RUBBER (US) | 2004-06-16 | — | — | EP | disclosed |
| US-6727374-B2 | TRIALKOXYSILYLHYDROCARBYL CYCLOHEXYL DISULFIDE, MADE BY REACTING N-CYCLOHEXYLTHIOPHTHALIMIDE AND A MERCAPTOALKOXYSILANE; SULFUR VULCANIZED RUBBER TIRES, BELTS AND HOSES | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-04-27 | — | — | US | disclosed |
| US-6593433-B2 | Alkoxysilylalkylammonium salts of alkoxysilylalkyl mercaptans used for processing sulfur-vuncanizable rubber compositions containing fillers | THE GOODYEAR TIRE & RUBBER COMPANY | 2003-07-15 | — | — | US | disclosed |
| US-6465670-B2 | SURFACE TREATMENT USING ORGANOSILICON COMPOUND, SOLVENT AND PHASE TRANSFER CATALYST | THE GOODYEAR TIRE & RUBBER COMPANY | 2002-10-15 | — | — | US | disclosed |
| US-20020022085-A1 | Preparation of surface modified silica | GOODYEAR TIRE & RUBBER COMPANY, THE | 2002-02-21 | — | — | US | disclosed |
| EP-1178077-A1 | The preparation of surface modified silica | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2002-02-06 | — | — | EP | disclosed |
| US-20020010239-A1 | Siloxy containing salt compounds | GOODYEAR TIRE & RUBBER COMPANY, THE | 2002-01-24 | — | — | US | disclosed |
| US-20010056142-A1 | Asymmetrical siloxy disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY. | 2001-12-27 | — | — | US | disclosed |
| US-6300397-B1 | MIXING SULFUR VULCANIZABLE ELASTOMER SELECTED FROM CONJUGATED DIENE HOMOPOLYMERS AND COPOLYMERS AND FROM COPOLYMERS OF CONJUGATED DIENE AND AROMATIC VINYL COMPOUND, PARTICULATE PRECIPITATED SILICA, SILOXY CYCLOHEXYL DISULFIDE COMPOUND | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-10-09 | — | — | US | disclosed |
| US-5760110-A | Process for the preparation of a particular reinforced rubber composition | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-06-02 | — | — | US | disclosed |
| EP-0794221-A1 | Process for the preparation of a particulate reinforced rubber composition | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-10 | — | — | EP | disclosed |
| US-5663358-A | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0785206-A1 | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-07-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010056142-A1 | Asymmetrical siloxy disulfide compounds | SULT1A1, QSOX1, TST | ALDH1A1 181/4885POLB 4262/4885MAPT 4474/4885 |
| US-20020022085-A1 | Preparation of surface modified silica | OSTC, SAMM50, SSRP1 | ALDH1A1 3796/4885POLB 1041/4885MAPT 1203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.