Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Carglumic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.69 |
| ▸ | NAALAD2 | Q9Y3Q0 | 5/20 | 0.69 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.69 |
| ▸ | GNPAT | O15228 | 1/20 | 0.49 |
| ▸ | GGH | Q92820 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carglumic Acid SCHEMBL373546 | 1.00 | FOLH1 (0.69) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| Carglumic Acid SCHEMBL910527 | 1.00 | FOLH1 (0.69) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| Carglumic Acid SCHEMBL27983953 | 1.00 | FOLH1 (0.69) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| Carglumic Acid SCHEMBL27983952 | 1.00 | FOLH1 (0.69) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| Carglumic Acid SCHEMBL27786751 | 0.98 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| Carglumic Acid SCHEMBL27772980 | 0.98 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| Carglumic Acid SCHEMBL28084488 | 0.98 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| Carglumic Acid SCHEMBL27786752 | 0.98 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| Carglumic Acid SCHEMBL27873856 | 0.98 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| Carglumic Acid SCHEMBL27890153 | 0.98 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLAGNPATGGH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 851 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119524462-B | Processing equipment and processing technology for N-carbamylglutamic acid | 锦州医科大学 | 2025-06-13 | — | — | CN | claimed |
| CN-119999817-A | Sheep feed based on silage tea leaves and preparation method and application thereof | 浙江工商大学 | 2025-05-16 | — | — | CN | claimed |
| CN-119404781-B | Bionic artificial propagation method for Dongxingqi | 海南晨海水产有限公司 | 2025-04-15 | — | — | CN | claimed |
| CN-119524462-A | Processing equipment and processing technology for NCG | 锦州医科大学 | 2025-02-28 | — | — | CN | claimed |
| CN-119523022-A | Nutritional additive for preventing and relieving livestock transportation stress and application thereof | 内蒙古自治区农牧业科学院 | 2025-02-28 | — | — | CN | claimed |
| CN-118318919-B | Composition for improving fish reproductive performance and application thereof | 中国水产科学研究院珠江水产研究所 | 2025-02-18 | — | — | CN | claimed |
| CN-119404969-A | Feed for improving intramuscular fat content of mutton, method and application thereof | 中国农业大学 | 2025-02-11 | — | — | CN | claimed |
| CN-119404781-A | Bionic artificial propagation method for Dongxingqi | 海南晨海水产有限公司 | 2025-02-11 | — | — | CN | claimed |
| CN-119054806-B | Feed additive for improving reproductive performance of ewes and application of feed additive | 吉林大学 | 2025-01-10 | — | — | CN | claimed |
| CN-119279099-A | Healthy and efficient compound feed based on gilts in Jia line | 新疆泰昆集团有限责任公司 | 2025-01-10 | — | — | CN | claimed |
| US-20110004019-A1 | Parakeratosis Inhibitor, Pore-Shrinking Agent, Or Rough Skin Inhibiting/Ameliorating Agent, And External Composition For Skin Containing The Same | SHISEIDO COMPANY LTD. (JP) | 2011-01-06 | — | — | US | claimed |
| EP-2255780-A1 | PARAKERATOSIS INHIBITOR, PORE SHRINKING AGENT OR AGENT FOR PREVENTING OR IMPROVING ROUGH SKIN, AND COMPOSITION FOR EXTERNAL USE ON THE SKIN CONTAINING THE SAME | Shiseido Company, Ltd. (JP) | 2010-12-01 | — | — | EP | claimed |
| CN-101785534-A | Application of zinc glutamate and derivatives thereof as animal feed additive for promoting growth | GUANGZHOU INSIGHTER BIOTECHNOL | 2010-07-28 | — | — | CN | claimed |
| CN-101759603-A | Preparation method and application of feed additive N-carbamylglutamic acid | INST SUBTROPICAL AGRICULTUR | 2010-06-30 | — | — | CN | claimed |
| CN-101756042-A | Application of cupric glutamate or derivative thereof as animal growth promoting feed additive | GUANGZHOU INSIGHTER BIOTECHNOL | 2010-06-30 | — | — | CN | claimed |
| CN-100582090-C | Method for preparing N-carbamyl glutamic acid | YULONG YIN | 2010-01-20 | — | — | CN | claimed |
| CN-101595944-A | A kind of purposes of feed in promoting the pig growth that contains the N-carbamylglutamic acid | INST SUBTROPICAL AGRICULTUR (CN) | 2009-12-09 | — | — | CN | claimed |
| CN-101565385-A | Pigling intestinal tract nutrition regulation and control substance N-carbamoylglutamine and preparation method | INST SUBTROPICAL AGRICULTUR (CN) | 2009-10-28 | — | — | CN | claimed |
| CN-101440042-A | Preparation of N-carbamylglutamic | BEIJING LONGKE FANGZHOU BIOLOG (CN) | 2009-05-27 | — | — | CN | claimed |
| CN-101168518-A | Method for preparing N-carbamyl glutamic acid | YULONG YIN (CN) | 2008-04-30 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110004019-A1 | Parakeratosis Inhibitor, Pore-Shrinking Agent, Or Rough Skin Inhibiting/Ameliorating Agent, And External Composition For Skin Containing The Same | CUTA, GLRA3, ARGLU1 | FOLH1 4099/4885NAALAD2 1692/4885RIMKLA 881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.