Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436340 | 0.81 | ALDH1A1 (0.57) | ALDH1A1CYP3A4TP53ALOX15TSHR | |
| SCHEMBL9004469 | 0.77 | GFER (0.36) | ALDH1A1CYP3A4TP53ALOX15TSHR | |
| SCHEMBL17529734 | 0.76 | ALDH1A1 (0.41) | ALDH1A1ALOX15ALOX12 | |
| SCHEMBL5488548 | 0.76 | LPL (0.42) | ALDH1A1THRB | |
| SCHEMBL2954273 | 0.76 | TAAR1 (0.33) | — | |
| SCHEMBL31347670 | 0.76 | NR1H2 (0.43) | THRB | |
| SCHEMBL27755509 | 0.76 | NR1H2 (0.30) | THRB | |
| SCHEMBL6285109 | 0.75 | GFER (0.41) | ALDH1A1CYP3A4TP53ALOX15TSHR | |
| SCHEMBL4905134 | 0.75 | ALDH1A1 (0.64) | ALDH1A1CYP3A4TP53ALOX15TSHR | |
| SCHEMBL8826588 | 0.75 | IDO1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |