SCHEMBL5493570

SCHEMBL5493570

Nc1ccccc1Cc1nc2ncncc2[nH]1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.45
METAP1 P53582 1/20 0.45
KRAS P01116 1/20 0.37
NPY5R Q15761 1/20 0.37
ATP4A P20648 2/20 0.34
ATP4B P51164 2/20 0.34
GRIN2B Q13224 3/20 0.33
AR P10275 1/20 0.33
IDO1 P14902 1/20 0.33
GAA P10253 4/20 0.33
MAPT P10636 3/20 0.33
PKM P14618 2/20 0.33
LMNA P02545 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
KDM4E B2RXH2 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HTT P42858 1/20 0.32
HKDC1 Q2TB90 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL434619 0.80 GAA (0.53) METAP2METAP1NPY5RGRIN2BGAA
SCHEMBL852580 0.78 METAP2 (0.43) METAP2METAP1NPY5RATP4AATP4B
SCHEMBL1551604 0.74 METAP2 (0.44) METAP2METAP1NPY5R
SCHEMBL10602607 0.72 METAP2 (0.48) METAP2METAP1NPY5RGRIN2BRAB9A
SCHEMBL8332576 0.72 RAB9A (0.54) METAP2METAP1GRIN2BMAPTNPC1
SCHEMBL9936013 0.71 METAP2 (0.44) METAP2METAP1NPY5RGRIN2BALDH1A1
SCHEMBL10857663 0.71 METAP2 (0.44) METAP2METAP1NPY5R
SCHEMBL1193887 0.71 METAP2 (0.44) METAP2METAP1NPY5RGAALMNA
SCHEMBL9572857 0.71 METAP2 (0.44) METAP2METAP1NPY5R
SCHEMBL4957462 0.71 METAP2 (0.44) METAP2METAP1NPY5RLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113564052-A Microalgae directional culture solution and application thereof, device for preparing sludge hydrolysate and device for directionally culturing biomass-enriched microalgae 华东理工大学 2021-10-29 CN claimed
EP-1235921-B1 SUGARBEET REGENERATION AND TRANSFORMATION MONSANTO TECHNOLOGY LLC (US) 2007-03-14 EP claimed
EP-1235921-A2 SUGARBEET REGENERATION AND TRANSFORMATION MONSANTO COMPANY (US) 2002-09-04 EP claimed
US-20010042257-A1 Sugarbeet regeneration and transformation MONSANTO TECHNOLOGY LLC 2001-11-15 US claimed
WO-2001042480-A2 SUGARBEET REGENERATION AND TRANSFORMATION MONSANTO TECHNOLOGY LLC (US) 2001-06-14 WO claimed
CN-113564052-A Microalgae directional culture solution and application thereof, device for preparing sludge hydrolysate and device for directionally culturing biomass-enriched microalgae 华东理工大学 2021-10-29 CN disclosed
CN-106857259-B Method for constructing high-frequency regeneration system of cotyledon of plane barberry and application of high-frequency regeneration system 华中农业大学 2020-01-10 CN disclosed
EP-1235921-B1 SUGARBEET REGENERATION AND TRANSFORMATION MONSANTO TECHNOLOGY LLC (US) 2007-03-14 EP disclosed
EP-1235921-A2 SUGARBEET REGENERATION AND TRANSFORMATION MONSANTO COMPANY (US) 2002-09-04 EP disclosed
US-20010042257-A1 Sugarbeet regeneration and transformation MONSANTO TECHNOLOGY LLC 2001-11-15 US disclosed
WO-2001042480-A2 SUGARBEET REGENERATION AND TRANSFORMATION MONSANTO TECHNOLOGY LLC (US) 2001-06-14 WO disclosed