Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.59 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.48 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5489935 | 0.84 | PARP10 (0.56) | PARP10PARP15SCN3APARP14CD274 | |
| Carbamic Acid SCHEMBL5490629 | 0.83 | SCN3A (0.61) | PARP10PARP15KMT2AKDM4EGAA | |
| Carbamic Acid SCHEMBL5491782 | 0.82 | SCN3A (0.52) | PARP10PARP15KMT2AKDM4EGAA | |
| Carbamic Acid SCHEMBL5485774 | 0.79 | KMT2A (0.52) | PARP10PARP15KMT2AKDM4EGAA | |
| Carbamic Acid SCHEMBL5490727 | 0.78 | KMT2A (0.53) | KMT2AKDM4EGAAHTTSCN3A | |
| SCHEMBL6169432 | 0.77 | SCN3A (0.71) | PARP10PARP15SCN3ACD274KCNH2 | |
| SCHEMBL6169438 | 0.77 | SCN3A (0.71) | PARP10PARP15SCN3ACD274KCNH2 | |
| Carbamic Acid SCHEMBL5484597 | 0.77 | KMT2A (0.60) | KMT2AKDM4EGAAHTTSCN3A | |
| SCHEMBL6511884 | 0.77 | HTR2C (0.57) | PARP10PARP15KDM4ESCN3AKCNH2 | |
| SCHEMBL6511728 | 0.77 | HTR2C (0.57) | PARP10PARP15KDM4ESCN3AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687259-B1 | CYCLOPENTYL DERIVATES | NEWRON PHARM SPA (IT) | 2007-08-08 | — | — | EP | claimed |