Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.57 |
| ▸ | HTR2B | P41595 | 5/20 | 0.57 |
| ▸ | HTR2A | P28223 | 4/20 | 0.57 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.55 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511884 | 1.00 | HTR2C (0.57) | HTR2CHTR2BHTR2AGID4PARP15 | |
| SCHEMBL20510494 | 0.88 | HTR2C (0.71) | HTR2CHTR2BHTR2AGID4PARP15 | |
| SCHEMBL6511004 | 0.84 | KDM4E (0.68) | HTR2CHTR2BHTR2AGID4KDM4E | |
| Trifluoroacetic Acid SCHEMBL20510471 | 0.84 | HTR2C (0.65) | HTR2CHTR2BHTR2AGID4KDM4E | |
| SCHEMBL20510514 | 0.83 | HTR2C (0.69) | HTR2CHTR2BHTR2AGID4KDM4E | |
| SCHEMBL20510457 | 0.81 | HTR2C (0.69) | HTR2CHTR2BHTR2AGID4KDM4E | |
| SCHEMBL6507699 | 0.81 | KMT2A (0.57) | HTR2CHTR2BHTR2AGID4KDM4E | |
| SCHEMBL6513706 | 0.79 | GID4 (0.59) | HTR2CHTR2BHTR2AGID4KDM4E | |
| SCHEMBL6514406 | 0.77 | HTR2C (0.54) | HTR2CHTR2BHTR2AGID4KDM4E | |
| SCHEMBL6510966 | 0.77 | HTR2C (0.54) | HTR2CHTR2BHTR2AGID4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040108-A1 | PROLINAMIDE DERIVATIVES AS SODIUM AND/OR CALCIUM CHANNEL BLOCKERS OR SELECTIVE MAO-B INHIBITORS | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2005-05-06 | — | — | WO | disclosed |