Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 4/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.35 |
| ▸ | ITGAV | P06756 | 4/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.35 |
| ▸ | ITGB5 | P18084 | 4/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 8/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5490026 | 0.99 | CRHR1 (0.42) | CRHR1ITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL4551762 | 0.90 | RPS6KA3 (0.35) | CRHR1HCRTR1 | |
| SCHEMBL5494098 | 0.89 | CRHR1 (0.42) | CRHR1ITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL5495528 | 0.89 | RPS6KA3 (0.35) | CRHR1HCRTR1 | |
| SCHEMBL5490030 | 0.89 | CRHR1 (0.42) | CRHR1ITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL5490098 | 0.87 | MAPT (0.32) | — | |
| SCHEMBL4551887 | 0.86 | MAPK3 (0.35) | AOC3 | |
| SCHEMBL4551483 | 0.85 | MAPK14 (0.39) | CRHR1 | |
| SCHEMBL4551537 | 0.84 | MAPK14 (0.39) | CRHR1 | |
| SCHEMBL5490596 | 0.84 | CRHR1 (0.50) | CRHR1ITGB3ITGB1ITGAVITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |