Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 4/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.34 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5490030 | 0.99 | CRHR1 (0.42) | CRHR1MAPK14SMONPC1RAB9A | |
| SCHEMBL4551483 | 0.95 | MAPK14 (0.39) | CRHR1MAPK14SMOMAPK13MAPK12 | |
| SCHEMBL4551537 | 0.95 | MAPK14 (0.39) | CRHR1MAPK14SMOMAPK13MAPK12 | |
| SCHEMBL14534448 | 0.91 | HCAR3 (0.40) | MAPK14SMONPC1RAB9AMAPT | |
| SCHEMBL4551763 | 0.90 | MAPK14 (0.39) | MAPK14SMONPC1RAB9AMAPT | |
| SCHEMBL5494096 | 0.89 | CRHR1 (0.42) | CRHR1ITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL5495529 | 0.89 | MAPK14 (0.39) | MAPK14SMONPC1RAB9AMAPT | |
| SCHEMBL5490026 | 0.89 | CRHR1 (0.42) | CRHR1ITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL5490107 | 0.87 | MAPK14 (0.39) | MAPK14SMONPC1RAB9AMAPT | |
| SCHEMBL5490598 | 0.87 | CRHR1 (0.50) | CRHR1MAPK14SMONPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |