Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.30 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.30 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551762 | 0.99 | RPS6KA3 (0.35) | RPS6KA3HCAR3HCAR2HRH4HCRTR1 | |
| SCHEMBL5490098 | 0.92 | MAPT (0.32) | RXFP1GRM5SLC6A9SLC6A5 | |
| SCHEMBL5495529 | 0.90 | MAPK14 (0.39) | — | |
| SCHEMBL5490026 | 0.90 | CRHR1 (0.42) | HCRTR1CRHR1SLC6A9SLC6A5 | |
| SCHEMBL4551763 | 0.89 | MAPK14 (0.39) | RPS6KA3 | |
| SCHEMBL5494096 | 0.89 | CRHR1 (0.42) | HCRTR1CRHR1 | |
| SCHEMBL4551887 | 0.85 | MAPK3 (0.35) | SLC6A9SLC6A5 | |
| SCHEMBL4541431 | 0.84 | MAPT (0.41) | RPS6KA3HCAR3HCAR2CRHR1 | |
| SCHEMBL4416933 | 0.83 | MAPK14 (0.43) | — | |
| SCHEMBL4552349 | 0.83 | MAPT (0.40) | RPS6KA3HCAR3HCAR2CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |