Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28084072 | 0.70 | TSHR (0.39) | TSHRUSP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL4529406 | 0.68 | TSHR (0.33) | TSHRUSP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL4958757 | 0.68 | — | — | |
| SCHEMBL5494147 | 0.64 | TSHR (0.31) | TSHRUSP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL2725107 | 0.64 | TSHR (0.31) | TSHRUSP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL5169910 | 0.61 | TSHR (0.39) | TSHRCYP2C19 | |
| Sulfuric Acid SCHEMBL5465130 | 0.61 | TSHR (0.39) | TSHRBLMCYP2C19 | |
| Sulfuric Acid SCHEMBL4208350 | 0.61 | CYP1A2 (0.48) | TSHRUSP2ALDH1A1LMNACYP1A2 | |
| Bicarbonate SCHEMBL29148107 | 0.60 | TSHR (0.42) | TSHRUSP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL744894 | 0.58 | NSD2 (0.48) | TSHRUSP2ALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070287706-A1 | Certain substituted quinolones, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287706-A1 | Certain substituted quinolones, compositions, and uses thereof | ABCG2, ATP5ME, ATP5MG | TSHR 4758/4885USP2 1282/4885ALDH1A1 1055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.