Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14974789 | 0.74 | ALDH1A1 (0.33) | TSHRCYP2C19USP2ALDH1A1LMNA | |
| SCHEMBL4529406 | 0.74 | TSHR (0.33) | TSHRCYP2C19USP2ALDH1A1LMNA | |
| SCHEMBL5494147 | 0.70 | TSHR (0.31) | TSHRCYP2C19USP2ALDH1A1LMNA | |
| SCHEMBL5494136 | 0.70 | TSHR (0.31) | TSHRCYP2C19USP2ALDH1A1LMNA | |
| SCHEMBL2725107 | 0.70 | TSHR (0.31) | TSHRCYP2C19USP2ALDH1A1LMNA | |
| SCHEMBL10888039 | 0.68 | TSHR (0.32) | TSHRCYP2C19 | |
| Bicarbonate SCHEMBL29148107 | 0.66 | TSHR (0.42) | TSHRCYP2C19USP2ALDH1A1LMNA | |
| SCHEMBL15095885 | 0.64 | NSD2 (0.48) | TSHRCYP2C19USP2ALDH1A1LMNA | |
| SCHEMBL744894 | 0.64 | NSD2 (0.48) | TSHRCYP2C19USP2ALDH1A1LMNA | |
| SCHEMBL21423145 | 0.64 | NSD2 (0.48) | TSHRCYP2C19USP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104159891-B | Pyridazine amide compound and they are as the purposes of SYK inhibitor | 霍夫曼-拉罗奇有限公司 | 2016-09-07 | — | — | CN | disclosed |