Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.52 |
| ▸ | DHODH | Q02127 | 2/20 | 0.50 |
| ▸ | IKBKB | O14920 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL10565823 | 0.84 | LMNA (0.48) | MAPTTSHRPOLBCYP3A4PARP1 | |
| Biphenyl SCHEMBL335359 | 0.83 | ALDH1A1 (0.60) | MAPTTSHRPOLBCYP3A4PARP1 | |
| Biphenyl SCHEMBL473288 | 0.83 | ALDH1A1 (0.60) | MAPTTSHRPOLBCYP3A4PARP1 | |
| Biphenyl SCHEMBL1952613 | 0.83 | ALDH1A1 (0.60) | MAPTTSHRPOLBCYP3A4PARP1 | |
| Biphenyl SCHEMBL4593266 | 0.83 | ALDH1A1 (0.60) | MAPTTSHRPOLBCYP3A4PARP1 | |
| Biphenyl SCHEMBL891497 | 0.83 | ALDH1A1 (0.69) | MAPTTSHRCYP3A4HSD17B10TDP1 | |
| Biphenyl SCHEMBL15518607 | 0.82 | LMNA (0.46) | MAPTTSHRPOLBCYP3A4PARP1 | |
| Biphenyl SCHEMBL15518995 | 0.82 | LMNA (0.46) | MAPTTSHRPOLBCYP3A4PARP1 | |
| Biphenyl SCHEMBL3276083 | 0.82 | TSHR (0.50) | MAPTTSHRCYP2C19BCAT2LMNA | |
| Biphenyl SCHEMBL5143620 | 0.80 | ALDH1A1 (0.56) | MAPTTSHRPOLBCYP3A4PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368021-B1 | CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING BIPOLAR DISORDER | ORTHO MCNEIL PHARM INC (US) | 2007-11-14 | — | — | EP | disclosed |
| EP-1399144-B1 | CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING ANXIETY DISORDERS | ORTHO MCNEIL PHARM INC (US) | 2006-04-26 | — | — | EP | disclosed |