Biphenyl

Biphenyl

SCHEMBL473288

NC(=O)O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.60
LMNA P02545 2/20 0.56
MAPT P10636 2/20 0.55
CYP3A4 P08684 2/20 0.55
TSHR P16473 2/20 0.55
HSD17B10 Q99714 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
POLB P06746 1/20 0.55
PARP1 P09874 1/20 0.55
CYP2C19 P33261 1/20 0.55
RECQL P46063 1/20 0.55
BLM P54132 1/20 0.55
PMP22 Q01453 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
BCAT2 O15382 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.52
WDR5 P61964 1/20 0.52
DHODH Q02127 2/20 0.52
IKBKB O14920 1/20 0.52
ABCC4 O15439 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL4593266 1.00 ALDH1A1 (0.60) ALDH1A1LMNAMAPTCYP3A4TSHR
Biphenyl SCHEMBL1952613 0.93 ALDH1A1 (0.60) ALDH1A1LMNAMAPTCYP3A4TSHR
Biphenyl SCHEMBL335359 0.93 ALDH1A1 (0.60) ALDH1A1LMNAMAPTCYP3A4TSHR
Biphenyl SCHEMBL5143620 0.90 ALDH1A1 (0.56) ALDH1A1LMNAMAPTCYP3A4TSHR
Biphenyl SCHEMBL11184429 0.88 ALDH1A1 (0.53) ALDH1A1LMNAMAPTCYP3A4TSHR
Biphenyl SCHEMBL310004 0.88 ALDH1A1 (0.53) ALDH1A1LMNAMAPTCYP3A4TSHR
Biphenyl SCHEMBL2670012 0.88 MAPT (0.61) ALDH1A1LMNAMAPTCYP3A4TSHR
Biphenyl SCHEMBL6469097 0.88 ALDH1A1 (0.53) ALDH1A1LMNAMAPTCYP3A4TSHR
Biphenyl SCHEMBL5573670 0.87 ALDH1A1 (0.60) ALDH1A1LMNAMAPTCYP3A4TSHR
Biphenyl SCHEMBL190337 0.86 ALDH1A1 (0.69) ALDH1A1LMNAMAPTTSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022049604-A1 PROCESS FOR PREPARING REVEFENACIN AND INTERMEDIATES THEROF CIPLA LIMITED (IN) 2022-03-10 WO claimed
US-20190161491-A1 METHODS FOR THE CHEMICAL SYNTHESIS OF PYRROLE-LINKED BIVALENT COMPOUNDS, AND COMPOSITIONS THEREOF AVEKSHAN, LLC. 2019-05-30 US claimed
US-20180072747-A1 METHODS FOR THE CHEMICAL SYNTHESIS OF PYRROLE-LINKED BIVALENT COMPOUNDS, AND COMPOSITIONS THEREOF AVEKSHAN, LLC. 2018-03-15 US claimed
EP-3270916-A1 METHODS FOR THE CHEMICAL SYNTHESIS OF PYRROLE-LINKED BIVALENT COMPOUNDS, AND COMPOSITIONS THEREOF Avekshan LLC (US) 2018-01-24 EP claimed
WO-2016149608-A1 METHODS FOR THE CHEMICAL SYNTHESIS OF PYRROLE-LINKED BIVALENT COMPOUNDS, AND COMPOSITIONS THEREOF AVEKSHAN LLC (US) 2016-09-22 WO claimed
EP-1301464-A1 BIPHENYLCARBOXYLIC ACID AMIDES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS Boehringer Ingelheim Pharma KG (DE) 2003-04-16 EP claimed
WO-2002004403-A1 BIPHENYLCARBOXYLIC ACID AMIDES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-01-17 WO claimed
EP-3527600-B1 ISOCYANATE COMPOSITION AND PRODUCTION METHOD FOR ISOCYANATE POLYMER ASAHI CHEMICAL IND (JP) 2025-07-09 EP disclosed
EP-3795561-B1 METHOD FOR PRODUCING CARBAMATE AND METHOD FOR PRODUCING ISOCYANATE ASAHI CHEMICAL IND (JP) 2024-11-06 EP disclosed
EP-4446310-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND Asahi Kasei Kabushiki Kaisha (JP) 2024-10-16 EP disclosed
CN-110105434-B Stapled and stitched polypeptides and uses thereof 哈佛大学的校长及成员们 2024-09-17 CN disclosed
CN-118382612-A Method for producing blocked isocyanate compound and method for producing isocyanate compound 旭化成株式会社 2024-07-23 CN disclosed
US-12037586-B2 4′-phosphate analogs and oligonucleotides comprising the same DICERNA PHARMACEUTICALS, INC. (US) 2024-07-16 US disclosed
US-4618363-A N-phenylsulfonyl-N'-triazinylureas CIBA-GEIGY CORPORATION (US) 1986-10-21 US disclosed
US-4579904-A DENTAL RESTORATIVES AND PILLING MATERIALS BLENDAX WERKE R. SCHNEIDER GMBH & CO. (DE) 1986-04-01 US disclosed
EP-0077036-B1 BINDING AGENT COMPOSITIONS UNION CARBIDE CORPORATION (US) 1986-01-08 EP disclosed
US-4419121-A HERBICIDES CIBA-GEIGY CORPORATION (US) 1983-12-06 US disclosed
EP-0077036-A1 Binding agent compositions UNION CARBIDE CORPORATION (US) 1983-04-20 EP disclosed
US-4366102-A Process for the preparation of chloroformic acid aryl esters BAYER AKTIENGESELLSCHAFT (DE) 1982-12-28 US disclosed
US-4046794-A ANCHORING AGENTS ON GLASS UNION CARBIDE CORPORATION (US) 1977-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180072747-A1 METHODS FOR THE CHEMICAL SYNTHESIS OF PYRROLE-LINKED BIVALENT COMPOUNDS, AND COMPOSITIONS THEREOF PAICS, TET3, PIN1 ALDH1A1 3424/4885LMNA 4125/4885MAPT 949/4885
US-20190161491-A1 METHODS FOR THE CHEMICAL SYNTHESIS OF PYRROLE-LINKED BIVALENT COMPOUNDS, AND COMPOSITIONS THEREOF PAICS, TET3, PIN1 ALDH1A1 3424/4885LMNA 4125/4885MAPT 949/4885
US-12037586-B2 4′-phosphate analogs and oligonucleotides comprising the same RNGTT, DERA, MTAP ALDH1A1 3655/4885LMNA 3570/4885MAPT 4596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.