Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16229736 | 1.00 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1SLC18A3GAAMEN1 | |
| SCHEMBL25045154 | 1.00 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1SLC18A3GAAMEN1 | |
| Water SCHEMBL28036374 | 0.98 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1SLC18A3 | |
| SCHEMBL24477812 | 0.98 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1SLC18A3 | |
| SCHEMBL21949021 | 0.93 | — | — | |
| SCHEMBL24147130 | 0.93 | — | — | |
| SCHEMBL21947980 | 0.93 | — | — | |
| SCHEMBL19043885 | 0.83 | — | — | |
| SCHEMBL18595190 | 0.83 | CA1 (0.38) | ALDH1A1L3MBTL1SLC18A3TRPA1 | |
| SCHEMBL7882602 | 0.83 | CA1 (0.38) | ALDH1A1L3MBTL1SLC18A3TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230054411-A1 | 7-, 8-, and 10-SUBSTITUTED AMINO TRIAZOLO QUINAZOLINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE | MERCK SHARP & DOHME CORP. (US) | 2023-02-23 | — | — | US | disclosed |
| US-7208548-B2 | Crosslinkable rubber compositions and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2007-04-24 | — | — | US | disclosed |
| EP-1088855-B1 | CROSSLINKABLE RUBBER COMPOSITION AND USE THEREOF | MITSUI CHEMICALS INC (JP) | 2007-02-28 | — | — | EP | disclosed |
| US-20050154132-A1 | Crosslinkable rubber compositions and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2005-07-14 | — | — | US | disclosed |
| US-6864315-B1 | Crosslinkable rubber compositions and use thereof | MITSUI CHEMICALS, INC. (JP) | 2005-03-08 | — | — | US | disclosed |
| EP-1088855-A1 | CROSSLINKABLE RUBBER COMPOSITION AND USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2001-04-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230054411-A1 | 7-, 8-, and 10-SUBSTITUTED AMINO TRIAZOLO QUINAZOLINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE | ADORA2A, ADORA2B, ADORA3 | ALDH1A1 1156/4885L3MBTL1 4506/4885SLC18A3 932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.