SCHEMBL5494638

SCHEMBL5494638

NC(=O)CNC(=O)C1CCCN1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PRCP P42785 3/20 0.54
TERT O14746 1/20 0.48
HTR2C P28335 5/20 0.47
HTR2B P41595 2/20 0.47
NOS2 P35228 2/20 0.46
NOS3 P29474 1/20 0.46
NOS1 P29475 1/20 0.46
KDM4E B2RXH2 1/20 0.44
TLR2 O60603 2/20 0.42
DPP7 Q9UHL4 1/20 0.41
GLI1 P08151 1/20 0.39
HTR2A P28223 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2197361 1.00 PRCP (0.54) PRCPTERTHTR2CHTR2BNOS2
SCHEMBL8789836 1.00 PRCP (0.54) PRCPTERTHTR2CHTR2BNOS2
Hydrochloric Acid SCHEMBL7702578 0.98 PRCP (0.53) PRCPTERTHTR2CHTR2BNOS2
Hydrochloric Acid SCHEMBL11516357 0.98 PRCP (0.53) PRCPTERTHTR2CHTR2BNOS2
Glycine SCHEMBL7541811 0.92 PRCP (0.48) PRCPTERTHTR2CHTR2BNOS2
SCHEMBL5959019 0.84 PRCP (0.44) PRCPTERTHTR2CHTR2BKDM4E
SCHEMBL620066 0.84 PRCP (0.55) PRCPTERTHTR2CHTR2BKDM4E
SCHEMBL620067 0.84 PRCP (0.55) PRCPTERTHTR2CHTR2BKDM4E
SCHEMBL8789170 0.84 PRCP (0.55) PRCPTERTHTR2CHTR2BKDM4E
SCHEMBL943040 0.83 PRCP (0.58) PRCPTERTHTR2CHTR2BNOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230173076-A1 METABOLICALLY STABLE PEPTIDE ANALOGS UNIV STRASBOURG (FR) 2023-06-08 US disclosed
US-7309689-B2 Sustained peptide-release formulation PEPTECH LIMITED (AU) 2007-12-18 US disclosed
WO-2004087190-A1 METHOD FOR THE TREATMENT OF PROSTATE CANCER GENIX THERAPEUTICS INC. (US) 2004-10-14 WO disclosed
US-6337318-B1 DRUGS FOR PEPTIDE AGONIST PEPTECH, LTD. (AU) 2002-01-08 US disclosed
EP-0021234-B1 NONAPEPTIDE AND DECAPEPTIDE DERIVATIVES OF LUTEINIZING HORMONE RELEASING HORMONE, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SYNTEX (U.S.A.) INC. (US) 1984-08-22 EP disclosed
US-RE29732-E Tripeptide ABBOTT LABORATORIES (US) 1978-08-15 US disclosed
US-4086219-A LUTEINIZING HORMONE RELEASING FACTOR ANTAGONISTS PARKE, DAVIS & COMPANY (US) 1978-04-25 US disclosed
US-3953416-A Synthetic decapeptide having the activity of the luteinizing hormone releasing hormone and method for manufacturing the same FOLKERS KARL 1976-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230173076-A1 METABOLICALLY STABLE PEPTIDE ANALOGS GPR119, GLP1R, GIPR PRCP 628/4885TERT 4493/4885HTR2C 760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.