SCHEMBL2197361

SCHEMBL2197361

NC(=O)CNC(=O)[C@@H]1CCCN1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PRCP P42785 3/20 0.54
TERT O14746 1/20 0.48
HTR2C P28335 5/20 0.47
HTR2B P41595 2/20 0.47
NOS2 P35228 2/20 0.46
NOS3 P29474 1/20 0.46
NOS1 P29475 1/20 0.46
KDM4E B2RXH2 1/20 0.44
TLR2 O60603 2/20 0.42
DPP7 Q9UHL4 1/20 0.41
GLI1 P08151 1/20 0.39
HTR2A P28223 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5494638 1.00 PRCP (0.54) PRCPTERTHTR2CHTR2BNOS2
SCHEMBL8789836 1.00 PRCP (0.54) PRCPTERTHTR2CHTR2BNOS2
Hydrochloric Acid SCHEMBL7702578 0.98 PRCP (0.53) PRCPTERTHTR2CHTR2BNOS2
Hydrochloric Acid SCHEMBL11516357 0.98 PRCP (0.53) PRCPTERTHTR2CHTR2BNOS2
Glycine SCHEMBL7541811 0.92 PRCP (0.48) PRCPTERTHTR2CHTR2BNOS2
SCHEMBL5959019 0.84 PRCP (0.44) PRCPTERTHTR2CHTR2BKDM4E
SCHEMBL620066 0.84 PRCP (0.55) PRCPTERTHTR2CHTR2BKDM4E
SCHEMBL620067 0.84 PRCP (0.55) PRCPTERTHTR2CHTR2BKDM4E
SCHEMBL8789170 0.84 PRCP (0.55) PRCPTERTHTR2CHTR2BKDM4E
SCHEMBL943040 0.83 PRCP (0.58) PRCPTERTHTR2CHTR2BNOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4688843-A1 GNRH-BINDING POLYPEPTIDES AND USES THEREOF 272Bio Limited (GB) 2026-02-11 EP claimed
US-12521395-B2 Gem-disubstituted heterocyclic compounds and their use as IDH inhibitors NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2026-01-13 US claimed
EP-4055015-B1 GEM-DISUBSTITUTED HETEROCYCLIC COMPOUNDS AND THEIR USE AS IDH INHIBITORS NERVIANO MEDICAL SCIENCES SRL (IT) 2025-04-02 EP claimed
WO-2024200846-A1 GNRH-BINDING POLYPEPTIDES AND USES THEREOF 272BIO Limited (GB) 2024-10-03 WO claimed
US-20240299511-A1 AN IMMUNOGEN UNIVERSITY OF PRETORIA (ZA) 2024-09-12 US claimed
EP-4284419-A1 AN IMMUNOGEN University Of Pretoria (ZA) 2023-12-06 EP claimed
US-20230000871-A1 GEM-DISUBSTITUTED HETEROCYCLIC COMPOUNDS AND THEIR USE AS IDH INHIBITORS NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2023-01-05 US claimed
US-11491140-B2 1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors H. LUNDBECK A/S (DK) 2022-11-08 US claimed
EP-4055015-A1 GEM-DISUBSTITUTED HETEROCYCLIC COMPOUNDS AND THEIR USE AS IDH INHIBITORS Nerviano Medical Sciences S.r.l. (IT) 2022-09-14 EP claimed
WO-2022162539-A1 AN IMMUNOGEN UNIVERSITY OF PRETORIA (ZA) 2022-08-04 WO claimed
US-20060217316-A1 Method for the treatment of prostate cancer GENIX THERAPEUTICS, INC. 2006-09-28 US claimed
WO-2004087190-A1 METHOD FOR THE TREATMENT OF PROSTATE CANCER GENIX THERAPEUTICS INC. (US) 2004-10-14 WO claimed
US-4493828-A Use of thyrotropin releasing hormone and related peptides as poultry growth promotants MERCK & CO., INC. (US) 1985-01-15 US claimed
US-3953416-A Synthetic decapeptide having the activity of the luteinizing hormone releasing hormone and method for manufacturing the same FOLKERS KARL 1976-04-27 US claimed
US-12590089-B2 Processes for preparing toll-like receptor modulator compounds GILEAD SCIENCES, INC. (US) 2026-03-31 US disclosed
US-12581252-B2 Substituted pyrrolo[3,4-b]pyridines as PI3K-α inhibitors RELAY THERAPEUTICS, INC. (US) 2026-03-17 US disclosed
EP-4688843-A1 GNRH-BINDING POLYPEPTIDES AND USES THEREOF 272Bio Limited (GB) 2026-02-11 EP disclosed
US-3953416-A Synthetic decapeptide having the activity of the luteinizing hormone releasing hormone and method for manufacturing the same FOLKERS KARL 1976-04-27 US disclosed
US-3947569-A Process for preparing the releasing hormone of luteinizing hormone (LH) and of follicle stimulating hormone (FSH), salts and compositions thereof, and intermediates therefor AMERICAN HOME PRODUCTS CORPORATION (US) 1976-03-30 US disclosed
US-3835108-A PROCESS FOR PREPARING THE RELEASING HORMONE OF LUTEINIZING HORMONE(LH)AND OF FOLLICLE STIMULATING HORMONE(FSH),SALTS AND COMPOSITIONS THEREOF,AND INTERMEDIATES THEREFOR AMERICAN HOME PROD 1974-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590089-B2 Processes for preparing toll-like receptor modulator compounds TLR8, MYD88, TLR6 PRCP 1203/4885TERT 3958/4885HTR2C 2860/4885
US-11491140-B2 1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors PDE3A, PDE5A, PDE12 PRCP 1530/4885TERT 3419/4885HTR2C 254/4885
US-20230000871-A1 GEM-DISUBSTITUTED HETEROCYCLIC COMPOUNDS AND THEIR USE AS IDH INHIBITORS IDH1, IDH2, IDH3A PRCP 2951/4885TERT 231/4885HTR2C 4190/4885
US-12581252-B2 Substituted pyrrolo[3,4-b]pyridines as PI3K-α inhibitors RORB, ROR1, RORA PRCP 3669/4885TERT 3959/4885HTR2C 1793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.