SCHEMBL5494819

SCHEMBL5494819

CC(C)(C)OC(=O)N(CC(=O)OCc1ccccc1)C(=O)[C@@H]1CCCN1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 2/20 0.41
HTR2B P41595 1/20 0.41
TSHR P16473 1/20 0.41
GLA P06280 1/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
SCN4A P35499 1/20 0.38
CTSL P07711 1/20 0.37
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
CTSC P53634 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPK1 P28482 1/20 0.36
KLK7 P49862 1/20 0.35
KLK5 Q9Y337 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7780012 0.85 HTR2C (0.40) HTR2CHTR2BTSHRL3MBTL1SCN4A
SCHEMBL29077734 0.81 L3MBTL1 (0.50) L3MBTL1ALDH1A1MAPK1KMT2A
SCHEMBL11304065 0.78 MAPT (0.43) HTR2CHTR2BL3MBTL1CTSLSIGMAR1
SCHEMBL28582403 0.77 SCN4A (0.44) HTR2CHTR2BTSHRL3MBTL1SCN4A
SCHEMBL3165698 0.76 CTSC (0.43) HTR2CHTR2BTSHRL3MBTL1SCN4A
SCHEMBL7273204 0.76 HTR2C (0.43) HTR2CHTR2BTSHRL3MBTL1SCN4A
SCHEMBL6687688 0.75 L3MBTL1 (0.43) HTR2CTSHRL3MBTL1SIGMAR1ALDH1A1
SCHEMBL13150768 0.74 L3MBTL1 (0.43) L3MBTL1ALDH1A1MAPK1
SCHEMBL1710041 0.74 L3MBTL1 (0.43) L3MBTL1ALDH1A1MAPK1MEN1KMT2A
SCHEMBL27396622 0.74 L3MBTL1 (0.43) L3MBTL1ALDH1A1MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159622-A1 COLLAGEN MIMICS WISCONSIN ALUMNI RESEARCH FOUNDATION 2023-05-25 US disclosed
US-11390662-B2 Collagen mimics WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2022-07-19 US disclosed
US-10329341-B2 Collagen mimics WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2019-06-25 US disclosed
US-20180030115-A1 COLLAGEN MIMICS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2018-02-01 US disclosed
US-9758569-B2 Collagen mimics WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2017-09-12 US disclosed
US-20070275897-A1 Collagen mimics NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-11-29 US disclosed