Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 2/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | YAP1 | P46937 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27735771 | 0.83 | ITGB3 (0.45) | CTSCITGB3ITGA2BHTR2CHTR2B | |
| SCHEMBL5163365 | 0.81 | ITGA4 (0.42) | CTSCSCN4A | |
| SCHEMBL9321962 | 0.80 | ATM (0.45) | L3MBTL1CYP1A2ACE | |
| SCHEMBL8392929 | 0.80 | ATM (0.45) | L3MBTL1CYP1A2ACE | |
| SCHEMBL11651226 | 0.80 | ATM (0.45) | L3MBTL1CYP1A2ACE | |
| SCHEMBL31593391 | 0.79 | CTSC (0.40) | CTSCITGB3ITGA2BHTR2CHTR2B | |
| SCHEMBL10790231 | 0.79 | CTSC (0.40) | CTSCHTR2CHTR2BL3MBTL1GHSR | |
| SCHEMBL28958862 | 0.78 | ATM (0.43) | L3MBTL1CYP1A2ACE | |
| SCHEMBL27514790 | 0.78 | ITGB3 (0.33) | ITGB3ITGA2BSCN4A | |
| SCHEMBL27565204 | 0.77 | CTSC (0.47) | CTSCHTR2CHTR2BSCN4AGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817109-B1 | MIXED-MODAL ANION-EXCHANGE TYPE SEPARATION MATERIAL | MERCK PATENT GMBH (DE) | 2020-02-26 | — | — | EP | disclosed |
| US-7648636-B2 | A chromatographic support including an immobilized ligand which combines an anion-exchange domain comprising an oligocyclic aza compound with endocyclic nitrogen and a non-ionic, second binding domain to allow adjustment of the overall hydrophobicity/hydrophilicity; separation; purification; peptides | MERCK PATENT GMBH (DE) | 2010-01-19 | — | — | US | disclosed |
| US-20080164211-A1 | Mixed-Modal Anion-Exchanged Type Separation Material | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | US | disclosed |
| EP-1817109-A1 | MIXED-MODAL ANION-EXCHANGE TYPE SEPARATION MATERIAL | Merck Patent GmbH (DE) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006058623-A1 | MIXED-MODAL ANION-EXCHANGE TYPE SEPARATION MATERIAL | MERCK PATENT GMBH (DE) | 2006-06-08 | — | — | WO | disclosed |