SCHEMBL549490

SCHEMBL549490

O=C(N/N=C\c1ccccc1)C(=O)N/N=C/c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 1.00
KMT2A Q03164 6/20 1.00
RAB9A P51151 5/20 0.61
SMN1; SMN2 Q16637 3/20 0.59
NPC1 O15118 3/20 0.59
G6PD P11413 1/20 0.59
CYP1A2 P05177 1/20 0.59
CYP3A4 P08684 1/20 0.59
CYP2C9 P11712 1/20 0.59
CYP2C19 P33261 1/20 0.59
CTRC Q99895 1/20 0.58
ALDH1A1 P00352 2/20 0.58
NOX4 Q9NPH5 1/20 0.56
LMNA P02545 2/20 0.56
HDAC3 O15379 1/20 0.56
HDAC2 Q92769 1/20 0.56
HDAC8 Q9BY41 1/20 0.56
NCOR2 Q9Y618 1/20 0.56
MAPT P10636 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9067815 1.00 MEN1 (1.00) MEN1KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL333482 1.00 MEN1 (1.00) MEN1KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL78287 1.00 MEN1 (1.00) MEN1KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL5081924 0.91 MEN1 (0.82) MEN1KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL5081918 0.91 MEN1 (0.82) MEN1KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL4115183 0.87 MEN1 (0.77) MEN1KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL4115180 0.87 MEN1 (0.77) MEN1KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL31588094 0.87 MEN1 (0.77) MEN1KMT2ARAB9ASMN1; SMN2NPC1
Phenylsemicarbazone SCHEMBL11882629 0.83 MEN1 (0.71) MEN1KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL13496984 0.83 MEN1 (0.71) MEN1KMT2ARAB9ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 712 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0610155-A1 Stabilized polyamide compositions CIBA-GEIGY AG (CH) 1994-08-10 EP claimed
US-6391949-B1 None US disclosed
EP-4440846-A1 SPECIAL PLASTIC FILM FOR THE PRODUCTION OF SECURITY DOCUMENTS Covestro Deutschland AG (DE) 2024-10-09 EP disclosed
US-11859084-B2 Flame-retardant and color-stable polyamide molding compounds CLARIANT INTERNATIONAL LTD (CH) 2024-01-02 US disclosed
WO-2023099349-A1 SPECIAL PLASTIC FILM FOR THE PRODUCTION OF SECURITY DOCUMENTS COVESTRO DEUTSCHLAND AG (DE) 2023-06-08 WO disclosed
US-11053375-B2 Anticorrosive flame retardant formulations for thermoplastic polymers CLARIANT PLASTICS & COATINGS LTD (CH) 2021-07-06 US disclosed
CN-104508031-B Phosphite compositions 瑞士新集团有限公司 2020-10-16 CN disclosed
US-20200277491-A1 FLAME-RETARDANT AND COLOR-STABLE POLYAMIDE MOLDING COMPOUNDS CLARIANT PLASTICS & COATINGS LTD (CH) 2020-09-03 US disclosed
EP-1404768-B1 POLYURETHANE BASED BALLPOINT INKS BIC CORP (US) 2020-04-22 EP disclosed
US-20190153197-A1 Flame Retardant-Stabilizer Combination For Thermoplastic Polymers CLARIANT INTERNATIONAL LTD (CH) 2019-05-23 US disclosed
US-3992420-A STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1976-11-16 US disclosed
US-3971757-A STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1976-07-27 US disclosed
US-3966711-A 4-Alkyl-1,4-diaza-5-oxo-cycloheptanes and their 1-oxyls CIBA-GEIGY CORPORATION (US) 1976-06-29 US disclosed
US-3959413-A POLYOLEFIN STABILIZERS CIBA-GEIGY CORPORATION (US) 1976-05-25 US disclosed
US-3956427-A STABILIZERS CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed
US-3956298-A POLYMER STABILIZERS CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed
US-3944632-A Phosphoric acid anilides CIBA-GEIGY CORPORATION (US) 1976-03-16 US disclosed
US-3943098-A 1-Aza-4-thiacyclohexane-4,4-dioxide derivatives and their use as agents protecting against light rays CIBA-GEIGY CORPORATION (US) 1976-03-09 US disclosed
US-3943096-A Use of hydroxyphenylurethanes for stabilising elastomers CIBA-GEIGY CORPORATION (US) 1976-03-09 US disclosed
US-3939175-A STABILIZER CIBA-GEIGY CORPORATION (US) 1976-02-17 US disclosed