SCHEMBL333482

SCHEMBL333482

O=C(N/N=C/c1ccccc1)C(=O)N/N=C/c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 1.00
KMT2A Q03164 6/20 1.00
RAB9A P51151 5/20 0.61
SMN1; SMN2 Q16637 3/20 0.59
NPC1 O15118 3/20 0.59
G6PD P11413 1/20 0.59
CYP1A2 P05177 1/20 0.59
CYP3A4 P08684 1/20 0.59
CYP2C9 P11712 1/20 0.59
CYP2C19 P33261 1/20 0.59
CTRC Q99895 1/20 0.58
ALDH1A1 P00352 2/20 0.58
NOX4 Q9NPH5 1/20 0.56
LMNA P02545 2/20 0.56
HDAC3 O15379 1/20 0.56
HDAC2 Q92769 1/20 0.56
HDAC8 Q9BY41 1/20 0.56
NCOR2 Q9Y618 1/20 0.56
MAPT P10636 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9067815 1.00 MEN1 (1.00) MEN1KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL549490 1.00 MEN1 (1.00) MEN1KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL78287 1.00 MEN1 (1.00) MEN1KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL5081924 0.91 MEN1 (0.82) MEN1KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL5081918 0.91 MEN1 (0.82) MEN1KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL4115183 0.87 MEN1 (0.77) MEN1KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL4115180 0.87 MEN1 (0.77) MEN1KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL31588094 0.87 MEN1 (0.77) MEN1KMT2ARAB9ASMN1; SMN2NPC1
Phenylsemicarbazone SCHEMBL11882629 0.83 MEN1 (0.71) MEN1KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL13496984 0.83 MEN1 (0.71) MEN1KMT2ARAB9ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 478 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2141197-B1 Polypropylene composition with improved properties BOREALIS AG (AT) 2011-05-25 EP claimed
EP-2141197-A1 Polypropylene composition with improved properties Borealis AG (AT) 2010-01-06 EP claimed
US-12612541-B2 Refrigerant blends having low global warming potential THE CHEMOURS COMPANY FC, LLC (US) 2026-04-28 US disclosed
US-20260071109-A1 HEAT TRANSFER COMPOSITIONS COMPRISING R-1225YE(E), HFO-1234YF, R-32, R-125, AND CO2 THE CHEMOURS COMPANY FC, LLC (US) 2026-03-12 US disclosed
EP-4219648-B1 A METHOD OF REPLACING HFO-1234ZE(E) CHEMOURS CO FC LLC (US) 2025-12-10 EP disclosed
EP-3935126-B1 PROCESS AND METHODS FOR RECLAIMING FLAMMABLE AND NON-FLAMMABLE HYDROFLUORO-OLEFIN CONTAINING REFRIGERANTS CHEMOURS CO FC LLC (US) 2025-09-24 EP disclosed
EP-4051750-B1 HEAT TRANSFER FLUIDS FOR USE IN LOW TEMPERATURE CHILLER APPLICATIONS CHEMOURS CO FC LLC (US) 2025-08-13 EP disclosed
EP-4122995-B1 COMPOSITIONS CONTAINING DIFLUOROMETHANE, TETRAFLUOROPROPENE, AND CARBON DIOXIDE AND USES THEREOF CHEMOURS CO FC LLC (US) 2025-07-16 EP disclosed
US-12338385-B2 Use of E-1,1,1,4,4,4-hexafluoro-2-butene in heat pumps THE CHEMOURS COMPANY FC, LLC (US) 2025-06-24 US disclosed
CN-120041154-A Refrigerant mixture comprising difluoromethane, pentafluoroethane, tetrafluoroethane, tetrafluoropropene and carbon dioxide and use thereof 科慕埃弗西有限公司 2025-05-27 CN disclosed
EP-4538346-A2 HEAT TRANSFER COMPOSITIONS COMPRISING R-1225YE(E) The Chemours Company FC, LLC (US) 2025-04-16 EP disclosed
US-20070108403-A1 refrigerants as heat exchanger; comprising 1,1,1,4,4,5,5,5-octafluoro-2-pentene mixture E. I. DU PONT DE NEMOURS AND COMPANY 2007-05-17 US disclosed
WO-2007053697-A2 COMPOSITIONS COMPRISING FLUOROOLEFINS AND USES THEREOF E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-05-10 WO disclosed
US-7091280-B2 Stabilizer mixture of a tetramethylpiperidine compound and a compound containing a hydrazide group, particularly the adduct of 2 moles of propylene carbonate and 1 mole of hydrazine BAYER AKTIENGESELLSCHAFT (DE) 2006-08-15 US disclosed
WO-2006060093-A1 COMPOSITION WITH ENHANCED HEAT RESISTANCE PROPERTY UNION CARBIDE CHEMICALS AND PLASTICS TECHNOLOGY CORPORATION (US) 2006-06-08 WO disclosed
EP-1663641-A1 EASILY TEARABLE WINDING STRIP CONSISTING OF A CO-EXTRUDED FILM Tesa AG (DE) 2006-06-07 EP disclosed
US-20060116456-A1 Composition with enhanced heat resistance property UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC 2006-06-01 US disclosed
EP-1527110-A1 SOFT FLAME-RESISTANT WINDING FILM Tesa AG (DE) 2005-05-04 EP disclosed
WO-2005023541-A1 EASILY TEARABLE WINDING STRIP CONSISTING OF A CO-EXTRUDED FILM TESA AG (DE) 2005-03-17 WO disclosed
WO-2003085012-A1 SOFT FLAME-RESISTANT WINDING FILM TESA AG (DE) 2003-10-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071109-A1 HEAT TRANSFER COMPOSITIONS COMPRISING R-1225YE(E), HFO-1234YF, R-32, R-125, AND CO2 H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, SCO2, RPL38 MEN1 4180/4885KMT2A 4495/4885RAB9A 2487/4885
US-12612541-B2 Refrigerant blends having low global warming potential EXOSC9, RPSA, RPP30 MEN1 3664/4885KMT2A 2791/4885RAB9A 283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.