SCHEMBL5495087

SCHEMBL5495087

C=C(c1cc[c]cc1)c1cccc2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTK2B Q14289 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
NR4A1 P22736 1/20 0.44
NR4A2 P43354 1/20 0.44
NR4A3 Q92570 1/20 0.44
MMP3 P08254 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
PTPN1 P18031 1/20 0.40
CDC25B P30305 1/20 0.40
PLK1 P53350 1/20 0.40
ALDH1A1 P00352 5/20 0.37
HPGD P15428 4/20 0.37
MAPT P10636 3/20 0.37
HSP90AA1 P07900 1/20 0.37
HTT P42858 1/20 0.37
CYP1A2 P05177 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
POLB P06746 3/20 0.35
KMT2A Q03164 3/20 0.35
LMNA P02545 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1933651 0.85 NR4A1 (0.55) PTK2BL3MBTL1NR4A1NR4A2NR4A3
Benzene SCHEMBL28192675 0.85 NR4A1 (0.55) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL31371895 0.85 NR4A1 (0.55) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL1869296 0.80 PTK2B (0.59) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL18159929 0.80 GFER (0.50) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL7152744 0.79 ALDH1A1 (0.51) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL3164058 0.79 ALDH1A1 (0.55) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL20773217 0.79 SMN1; SMN2 (0.58) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL1127557 0.79 CDC25B (0.56) L3MBTL1NR4A1NR4A2NR4A3MMP3
SCHEMBL16549911 0.75 RAB9A (0.51) PTK2BL3MBTL1ALDH1A1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7303856-B2 Light-sensitive sheet comprising support, first light-sensitive layer and second light-sensitive layer FUJIFILM CORPORATION (JP) 2007-12-04 US disclosed
US-7150955-B2 Light-sensitive sheet comprising support, first and second light-sensitive layers and barrier layer FUJI PHOTO FILM CO., LTD. (JP) 2006-12-19 US disclosed
US-20050037281-A1 Light-sensitive sheet comprising support, first and second light-sensitive layers and barrier layer FUJI PHOTO FILM CO., LTD. 2005-02-17 US disclosed
EP-1507171-A2 Light-Sensitive sheet comprising support, first and second light-sensitive layers and barrier layer FUJI PHOTO FILM CO., LTD. (JP) 2005-02-16 EP disclosed
US-20050025946-A1 Light-sensitive sheet comprising support, first light-sensitive layer and second light-sensitive layer FUJI PHOTO FILM CO., LTD. 2005-02-03 US disclosed
EP-1489460-A2 Light-sensitive sheet comprising support, first light-sensitive layer and second light-sensitive layer Fuji Photo Film Co., Ltd. (JP) 2004-12-22 EP disclosed