SCHEMBL5495240

SCHEMBL5495240

C=CC12CC3CC(C1)CC(C=C)(C3)C2

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
KMT2A Q03164 1/20 0.32
NPFFR1 Q9GZQ6 1/20 0.31
NPFFR2 Q9Y5X5 1/20 0.31
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2A Q12879 1/20 0.31
GRIN2B Q13224 1/20 0.31
GRIN2C Q14957 1/20 0.31
GRIN3A Q8TCU5 1/20 0.31
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3843497 0.87
SCHEMBL3846937 0.85
SCHEMBL4437737 0.84 NPFFR1 (0.31) NPFFR1NPFFR2GRIN2DGRIN3BGRIN1
SCHEMBL6354923 0.84 PKM (0.47) MEN1ALDH1A1KMT2ANPFFR1NPFFR2
SCHEMBL4102744 0.82
SCHEMBL960382 0.82 GRIN2D (0.38) NPFFR1NPFFR2GRIN2DGRIN3BGRIN1
Water SCHEMBL4022360 0.80 NPFFR1 (0.37) NPFFR1NPFFR2GRIN2DGRIN3BGRIN1
SCHEMBL23051570 0.79 MEN1 (0.39) MEN1ALDH1A1KMT2AGRIN2DGRIN3B
SCHEMBL7733776 0.77
SCHEMBL3848004 0.77 LMNA (0.32) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110770282-A Curable silicone composition, and application and use thereof 莫门蒂夫性能材料股份有限公司 2020-02-07 CN claimed
US-10385210-B2 Curable silicone composition and applications and uses thereof MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2019-08-20 US claimed
US-10287400-B2 Curable silicone composition and applications and uses thereof MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2019-05-14 US claimed
EP-3443027-A1 CURABLE SILICONE COMPOSITION AND APPLICATIONS AND USES THEREOF Momentive Performance Materials Inc. (US) 2019-02-20 EP claimed
CN-109312077-A Curable silicon composition and its application and use 莫门蒂夫性能材料股份有限公司 2019-02-05 CN claimed
WO-2017180329-A1 CURABLE SILICONE COMPOSITION AND APPLICATIONS AND USES THEREOF MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2017-10-19 WO claimed
US-20170298188-A1 CURABLE SILICONE COMPOSITION AND APPLICATIONS AND USES THEREOF MOMENTIVE PERFORMANCE MATERIALS INC. 2017-10-19 US claimed
CN-110770282-A Curable silicone composition, and application and use thereof 莫门蒂夫性能材料股份有限公司 2020-02-07 CN disclosed
US-10287400-B2 Curable silicone composition and applications and uses thereof MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2019-05-14 US disclosed
EP-3443027-A1 CURABLE SILICONE COMPOSITION AND APPLICATIONS AND USES THEREOF Momentive Performance Materials Inc. (US) 2019-02-20 EP disclosed
CN-109312077-A Curable silicon composition and its application and use 莫门蒂夫性能材料股份有限公司 2019-02-05 CN disclosed
US-20170298188-A1 CURABLE SILICONE COMPOSITION AND APPLICATIONS AND USES THEREOF MOMENTIVE PERFORMANCE MATERIALS INC. 2017-10-19 US disclosed
WO-2017180329-A1 CURABLE SILICONE COMPOSITION AND APPLICATIONS AND USES THEREOF MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2017-10-19 WO disclosed
EP-0990634-B1 ACYLATING AGENTS, ACYLATION METHOD WITH THE USE OF THE SAME AND ADAMANTANE DERIVATIVES DAICEL CHEM (JP) 2013-04-10 EP disclosed
US-7309752-B2 Polymer and film forming composition FUJIFILM CORPORATION (JP) 2007-12-18 US disclosed
US-20070073019-A1 Polymer and film forming composition FUJI PHOTO FILM CO., LTD. 2007-03-29 US disclosed
US-6429314-B1 USING 1,2-DICARBONYL DERIVATIVE OR ITS HYDROXY REDUCTIVE, OXYGEN, COBALT ACETATE METAL COMPOUND, AND N-HYDROXYPHTHALIMIDE OR OTHER IMIDE DERIVATIVE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-08-06 US disclosed
EP-0990634-A1 ACYLATING AGENTS, ACYLATION METHOD WITH THE USE OF THE SAME AND ADAMANTANE DERIVATIVES Daicel Chemical Industries, Ltd. (JP) 2000-04-05 EP disclosed
US-4918158-A HEAT RESISTANCE; DIELECTRICS, MATRICES, AEROSPACE FLUOROCHEM INC. (US) 1990-04-17 US disclosed
US-4849565-A 1,3-diethynyladamantane and methods of polymerization thereof BAUM KURT (US) 1989-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170298188-A1 CURABLE SILICONE COMPOSITION AND APPLICATIONS AND USES THEREOF VCL, CCNI, SMCHD1 MEN1 2151/4885ALDH1A1 1443/4885KMT2A 2275/4885
US-10287400-B2 Curable silicone composition and applications and uses thereof VCL, CCNI, SMCHD1 MEN1 2151/4885ALDH1A1 1443/4885KMT2A 2275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.