Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | F2R | P25116 | 8/20 | 0.46 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.46 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.46 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL954535 | 0.92 | ITGB3 (0.56) | ITGB3ITGA2BF2RSLC6A1GABRA5 | |
| Hydrochloric Acid SCHEMBL3159636 | 0.90 | ITGB3 (0.54) | ITGB3ITGA2BF2RSLC6A1GABRA5 | |
| SCHEMBL5501220 | 0.89 | ITGB3 (0.59) | ITGB3ITGA2BKMT2AF2RSLC6A1 | |
| Acetic Acid SCHEMBL9210574 | 0.86 | ITGB3 (0.51) | ITGB3ITGA2BF2RSLC6A1GABRA5 | |
| SCHEMBL23909396 | 0.86 | ITGB3 (0.60) | ITGB3ITGA2BF2RSLC6A1GABRA5 | |
| SCHEMBL13308548 | 0.85 | KMT2A (0.62) | KMT2ASLC6A1GABRA5GABRB2SLC6A12 | |
| SCHEMBL2525645 | 0.85 | KMT2A (0.62) | KMT2ASLC6A1GABRA5GABRB2SLC6A12 | |
| SCHEMBL13308547 | 0.85 | KMT2A (0.62) | KMT2ASLC6A1GABRA5GABRB2SLC6A12 | |
| SCHEMBL15263859 | 0.83 | HPGD (0.50) | KMT2A | |
| Hydrochloric Acid SCHEMBL8182632 | 0.83 | KMT2A (0.60) | KMT2ASLC6A1GABRA5GABRB2SLC6A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070238721-A1 | Highly Selective Novel Amidation Method | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-10-11 | — | — | US | disclosed |
| EP-1753752-A1 | HIGHLY SELECTIVE NOVEL AMIDATION METHOD | Takeda Pharmaceutical Company Limited (JP) | 2007-02-21 | — | — | EP | disclosed |
| WO-2005121133-A1 | HIGHLY SELECTIVE NOVEL AMIDATION METHOD | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238721-A1 | Highly Selective Novel Amidation Method | NAAA, CPS1, COASY | ITGB3 4773/4885ITGA2B 4439/4885KMT2A 484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.