Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 9/20 | 0.53 |
| ▸ | PPARA | Q07869 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4681650 | 0.87 | FBP1 (0.54) | FBP1PPARATSHRABCB11CYP1A2 | |
| SCHEMBL4685610 | 0.85 | FBP1 (0.53) | FBP1PPARATSHRABCB11CYP1A2 | |
| SCHEMBL6081047 | 0.84 | FBP1 (0.52) | FBP1PPARATSHRABCB11CYP1A2 | |
| SCHEMBL3284352 | 0.84 | FBP1 (0.52) | FBP1PPARATSHRABCB11CYP1A2 | |
| SCHEMBL3484624 | 0.83 | FBP1 (0.51) | FBP1PPARATSHRABCB11CYP1A2 | |
| SCHEMBL5794671 | 0.81 | KDM4E (0.55) | PPARACYP1A2CYP3A4PPARGMEN1 | |
| SCHEMBL4111678 | 0.81 | FBP1 (0.58) | FBP1PPARATSHRABCB11CYP1A2 | |
| SCHEMBL12670823 | 0.80 | FBP1 (0.56) | FBP1PPARATSHRABCB11CYP1A2 | |
| SCHEMBL4423002 | 0.79 | PPARA (0.59) | FBP1PPARATSHRABCB11CYP1A2 | |
| SCHEMBL14092161 | 0.79 | FBP1 (0.55) | FBP1PPARATSHRABCB11CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167628-A1 | Thiazole-2-carboxamide derivatives for use as hippar agonists in the treatment of i.a. dyslipidemia | SMITHKLINE BEECHAM CORPORATION | 2007-07-19 | — | — | US | disclosed |
| US-20060079696-A1 | Substituted compounds derived from N-(benzyl)phenylacetamide, preparation and uses | GENFIT (FR) | 2006-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060079696-A1 | Substituted compounds derived from N-(benzyl)phenylacetamide, preparation and uses | AADAC, NAT1, PARN | FBP1 2946/4885PPARA 425/4885TSHR 4628/4885 |
| US-20070167628-A1 | Thiazole-2-carboxamide derivatives for use as hippar agonists in the treatment of i.a. dyslipidemia | GPR119, INSR, HCAR2 | FBP1 2419/4885PPARA 10/4885TSHR 140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.