Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 3/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | GPR4 | P46093 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5500050 | 0.91 | KCNH2 (0.43) | DPP4DAOHTR6KCNH2GPR4 | |
| Hydrochloric Acid SCHEMBL7983042 | 0.90 | KCNH2 (0.42) | DPP4DAOHTR6KCNH2GPR4 | |
| SCHEMBL5500258 | 0.87 | SIGMAR1 (0.38) | KCNH2CYP2D6RENDRD2 | |
| SCHEMBL5240121 | 0.84 | GRIN2B (0.41) | DPP4DAOHTR6ALDH1A1HTT | |
| SCHEMBL14790650 | 0.83 | KDM1A (0.38) | DPP4DAOMCHR1 | |
| Hydrochloric Acid SCHEMBL14840786 | 0.83 | GRIN2B (0.40) | DPP4DAOHTR6ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL14782698 | 0.82 | KDM1A (0.37) | DPP4DAOMCHR1 | |
| Hydrochloric Acid SCHEMBL14783269 | 0.82 | KDM1A (0.37) | DPP4DAOMCHR1 | |
| SCHEMBL5237164 | 0.82 | OPRM1 (0.39) | KCNH2GPR4ALDH1A1OPRM1OPRL1 | |
| SCHEMBL5505313 | 0.81 | KCNH2 (0.33) | HTR6KCNH2GPR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765779-A1 | NEW SUBSTITUTED PIPERIDINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005121092-A1 | NEW SUBSTITUTED PIPERIDINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2005-12-22 | — | — | WO | disclosed |