Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.67 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.59 |
| ▸ | FAAH | O00519 | 1/20 | 0.58 |
| ▸ | CNR2 | P34972 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5495794 | 1.00 | TRPV1 (0.67) | TRPV1SOAT1FAAHCNR2KDM4E | |
| SCHEMBL5495380 | 0.87 | TRPV1 (0.71) | TRPV1SOAT1FAAHCNR2KDM4E | |
| SCHEMBL5495385 | 0.87 | TRPV1 (0.71) | TRPV1SOAT1FAAHCNR2KDM4E | |
| SCHEMBL5494892 | 0.84 | ALDH1A1 (0.58) | TRPV1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL5494884 | 0.84 | ALDH1A1 (0.58) | TRPV1KDM4EALDH1A1HPGDGAA | |
| Fogaramide SCHEMBL17073972 | 0.83 | TRPV1 (0.84) | TRPV1SOAT1FAAHCNR2KDM4E | |
| Fogaramide SCHEMBL2987846 | 0.83 | TRPV1 (0.84) | TRPV1SOAT1FAAHCNR2KDM4E | |
| SCHEMBL5491714 | 0.83 | KDM4E (0.63) | TRPV1SOAT1CNR2KDM4EALDH1A1 | |
| SCHEMBL5492850 | 0.81 | CYP1A2 (0.57) | KDM4EALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL4270755 | 0.81 | CYP1A2 (0.57) | KDM4EALDH1A1HPGDCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9073860-B2 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-07-07 | — | — | US | claimed |
| US-20140073595-A1 | AROMATIC AMIDES AS POTENTIATORS OF BIOEFFICACY OF ANTI-INFECTIVE DRUGS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2014-03-13 | — | — | US | claimed |
| US-8580752-B2 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTITIC AND INDUSTRIAL RESEARCH (IN) | 2013-11-12 | — | — | US | claimed |
| US-20070004645-A1 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-01-04 | — | — | US | claimed |
| WO-2006103527-A1 | AROMATIC SUBSTITUTED PENTADIENOIC ACID AMIDE FOR COMBINATION WITH ANTI-INFECTIVE DRUGS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-10-05 | — | — | WO | claimed |
| US-9073860-B2 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-07-07 | — | — | US | disclosed |
| US-20140073595-A1 | AROMATIC AMIDES AS POTENTIATORS OF BIOEFFICACY OF ANTI-INFECTIVE DRUGS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2014-03-13 | — | — | US | disclosed |
| US-8580752-B2 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTITIC AND INDUSTRIAL RESEARCH (IN) | 2013-11-12 | — | — | US | disclosed |
| US-20070004645-A1 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140073595-A1 | AROMATIC AMIDES AS POTENTIATORS OF BIOEFFICACY OF ANTI-INFECTIVE DRUGS | DDC, APEH, AADAC | TRPV1 1550/4885SOAT1 1055/4885FAAH 47/4885 |
| US-20070004645-A1 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | DDC, APEH, AADAC | TRPV1 1550/4885SOAT1 1055/4885FAAH 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.