Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25859924 | 1.00 | SLC6A3 (0.49) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL5525427 | 0.98 | SLC6A3 (0.47) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL5502385 | 0.94 | SLC6A3 (0.42) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL5765094 | 0.94 | SLC6A3 (0.42) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| Hydrochloric Acid SCHEMBL336871 | 0.92 | SLC6A3 (0.41) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL11119178 | 0.87 | — | — | |
| SCHEMBL19124798 | 0.82 | SLC6A3 (0.44) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL11737778 | 0.81 | SLC6A3 (0.43) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL27353662 | 0.79 | SLC6A3 (0.42) | SLC6A3SLC6A2SLC6A4DHFR | |
| SCHEMBL6879567 | 0.79 | SLC6A3 (0.47) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308861-A | Tetrapyrole compounds | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1994-05-03 | — | — | US | claimed |
| WO-2018021977-A1 | GLYCINE METABOLISM MODULATORS AND USES THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-02-01 | — | — | WO | disclosed |
| US-20070238721-A1 | Highly Selective Novel Amidation Method | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-10-11 | — | — | US | disclosed |
| EP-1753752-A1 | HIGHLY SELECTIVE NOVEL AMIDATION METHOD | Takeda Pharmaceutical Company Limited (JP) | 2007-02-21 | — | — | EP | disclosed |
| EP-1084710-B1 | ADENOSINE A1 ANTAGONISTS FOR MALE STERILITY | ASTELLAS PHARMA INC (JP) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005121133-A1 | HIGHLY SELECTIVE NOVEL AMIDATION METHOD | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-12-22 | — | — | WO | disclosed |
| EP-1467760-A2 | SYSTEMS AND METHODS FOR PHOTODYNAMIC THERAPY | Light Sciences Corporation (US) | 2004-10-20 | — | — | EP | disclosed |
| US-20040152659-A1 | Method for the treatment of parkinson's disease comprising administering an A1A2a receptor dual antagonist | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2004-08-05 | — | — | US | disclosed |
| US-20030167033-A1 | Systems and methods for photodynamic therapy | LIGHT SCIENCES CORPORATION | 2003-09-04 | — | — | US | disclosed |
| WO-2003061696-A2 | SYSTEMS AND METHODS FOR PHOTODYNAMIC THERAPY | LIGHT SCIENCES CORPORATION (US) | 2003-07-31 | — | — | WO | disclosed |
| EP-0213272-B1 | NEW TETRAPYRROLE POLYAMINOMONOCARBOXYLIC ACID THERAPEUTIC AGENTS | Nippon Petrochemicals Co., Ltd. (JP) | 1992-09-09 | — | — | EP | disclosed |
| EP-0497258-A2 | Use of adenosine antagonists in the prevention and treatment of pancreatitis and ulcer | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-05 | — | — | EP | disclosed |
| EP-0200218-B1 | TETRAPYRROLE THERAPEUTIC AGENTS | Nippon Petrochemicals Co., Ltd. (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-4997639-A | Porphyrins | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1991-03-05 | — | — | US | disclosed |
| US-4977177-A | DETECTION AND TREATMENT OF TUMORS | NIPPON PETROCHEMICALS COMPANY, LTD. (JP) | 1990-12-11 | — | — | US | disclosed |
| US-4656186-A | FLUORESCENCE | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1987-04-07 | — | — | US | disclosed |
| EP-0213272-A2 | New tetrapyrrole polyaminomonocarboxylic acid therapeutic agents | Nippon Petrochemicals Co., Ltd. (JP) | 1987-03-11 | — | — | EP | disclosed |
| EP-0200218-A2 | Tetrapyrrole therapeutic agents | Nippon Petrochemicals Co., Ltd. (JP) | 1986-11-05 | — | — | EP | disclosed |
| US-4217238-A | BASIC SALT, SCRUBBING | EXXON RESEARCH & ENGINEERING CO. (US) | 1980-08-12 | — | — | US | disclosed |
| US-4094957-A | CARBON DIOXIDE | EXXON RESEARCH & ENGINEERING CO. (US) | 1978-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152659-A1 | Method for the treatment of parkinson's disease comprising administering an A1A2a receptor dual antagonist | ADORA2A, ADORA1, ADORA2B | SLC6A3 81/4885SLC6A2 45/4885SLC6A4 259/4885 |
| US-20070238721-A1 | Highly Selective Novel Amidation Method | NAAA, CPS1, COASY | SLC6A3 4741/4885SLC6A2 4647/4885SLC6A4 4405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.