Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL921135 | 0.76 | CA12 (0.41) | ALDH1A1TSHRMEN1KMT2ATP53 | |
| SCHEMBL5496057 | 0.76 | KDM4E (0.41) | ALDH1A1TSHRMEN1KMT2ATP53 | |
| SCHEMBL6930630 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TSHRMEN1KMT2ATP53 | |
| SCHEMBL28886962 | 0.75 | TSHR (0.41) | ALDH1A1TSHRMEN1KMT2ATP53 | |
| SCHEMBL31290457 | 0.74 | KDM4E (0.44) | ALDH1A1TSHRMEN1KMT2ATP53 | |
| SCHEMBL5491831 | 0.72 | MAPT (0.44) | ALDH1A1TSHRTP53MAPTHPGD | |
| SCHEMBL10888602 | 0.71 | TP53 (0.42) | ALDH1A1TSHRTP53POLBHPGD | |
| SCHEMBL15385450 | 0.71 | TSHR (0.38) | ALDH1A1TSHRMEN1KMT2ATP53 | |
| SCHEMBL10888595 | 0.71 | ALDH1A1 (0.36) | ALDH1A1TSHRMEN1KMT2ATP53 | |
| SCHEMBL3542930 | 0.70 | ALOX5 (0.46) | ALDH1A1TSHRMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1170295-B1 | Thiocarbonates as flavour precursors | QUEST INT (NL) | 2007-12-19 | — | — | EP | claimed |
| US-6852350-B2 | Flavor precursors | FITZ WOLFGANG (NL) | 2005-02-08 | — | — | US | claimed |
| US-20020037349-A1 | Flavour precursors | FITZ WOLFGANG (NL) | 2002-03-28 | — | — | US | claimed |
| EP-1170295-A1 | Thiocarbonates as flavour precursors | QUEST INTERNATIONAL NEDERLAND BV (NL) | 2002-01-09 | — | — | EP | claimed |
| EP-1170295-B1 | Thiocarbonates as flavour precursors | QUEST INT (NL) | 2007-12-19 | — | — | EP | disclosed |
| EP-1170295-B1 | Thiocarbonates as flavour precursors | QUEST INT (NL) | 2007-12-19 | — | — | EP | disclosed |
| US-6852350-B2 | Flavor precursors | FITZ WOLFGANG (NL) | 2005-02-08 | — | — | US | disclosed |
| US-20020037349-A1 | Flavour precursors | FITZ WOLFGANG (NL) | 2002-03-28 | — | — | US | disclosed |
| EP-1170295-A1 | Thiocarbonates as flavour precursors | QUEST INTERNATIONAL NEDERLAND BV (NL) | 2002-01-09 | — | — | EP | disclosed |