SCHEMBL5496428

SCHEMBL5496428

CSC(C(=O)CN1CCOCC1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
LMNA P02545 2/20 0.49
KDM4E B2RXH2 1/20 0.47
CYP3A4 P08684 1/20 0.47
HIF1A Q16665 1/20 0.47
USP2 O75604 1/20 0.47
HTT P42858 1/20 0.47
POLB P06746 1/20 0.46
MAPT P10636 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5617142 0.86 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2LMNAKDM4ECYP3A4
SCHEMBL28838516 0.72 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2LMNACYP3A4HIF1A
SCHEMBL5486112 0.71 OPRM1 (0.52) ALDH1A1SMN1; SMN2LMNAKDM4EUSP2
SCHEMBL12666562 0.69 GPR88 (0.52) ALDH1A1SMN1; SMN2LMNACYP3A4HIF1A
SCHEMBL3159167 0.69 ALDH1A1 (0.71) ALDH1A1SMN1; SMN2LMNAKDM4EHIF1A
SCHEMBL8203867 0.69 SMN1; SMN2 (0.44) ALDH1A1SMN1; SMN2LMNAKDM4EMAPT
SCHEMBL12284224 0.69 SMN1; SMN2 (0.65) ALDH1A1SMN1; SMN2LMNAHIF1AHTT
SCHEMBL12158507 0.68 KDM4E (0.55) ALDH1A1SMN1; SMN2LMNAKDM4EUSP2
SCHEMBL12000801 0.68 POLB (0.49) ALDH1A1SMN1; SMN2LMNAKDM4EUSP2
SCHEMBL19334158 0.68 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2LMNACYP3A4HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007067466-A2 DIGITAL PRINTING USING ULTRAVIOLET INKS GENERAL ELECTRIC COMPANY (US) 2007-06-14 WO claimed