Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 2/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5496671 | 1.00 | GSTP1 (1.00) | GSTP1CYP2C19TP53CYP3A4CYP2C9 | |
| SCHEMBL10824824 | 0.81 | GSTP1 (0.68) | GSTP1CYP2C19TP53CYP3A4CYP2C9 | |
| SCHEMBL23500877 | 0.80 | GSTP1 (0.67) | GSTP1CYP2C19TP53CYP3A4CYP2C9 | |
| SCHEMBL23500879 | 0.79 | GSTP1 (0.65) | GSTP1CYP2C19TP53CYP3A4CYP2C9 | |
| SCHEMBL23500188 | 0.77 | GSTP1 (0.62) | GSTP1LMNAKDM4EALDH1A1 | |
| SCHEMBL5706344 | 0.77 | GSTP1 (0.62) | GSTP1LMNAKDM4EALDH1A1 | |
| SCHEMBL5491232 | 0.76 | GSTP1 (0.61) | GSTP1CYP2C19TP53CYP3A4CYP2C9 | |
| SCHEMBL13715203 | 0.75 | GSTP1 (0.59) | GSTP1CYP2C19TP53CYP3A4ALOX15 | |
| SCHEMBL13715186 | 0.74 | GSTP1 (0.58) | GSTP1CYP2C19TP53CYP3A4CYP2C9 | |
| SCHEMBL27439058 | 0.73 | GSTP1 (0.57) | GSTP1CYP2C19TP53CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070287672-A1 | Macromolecular Gsh-Activiated Glyoxylase I Inhibitors | MARYLAND, UNIVERSITY OF, BALTIMORE COUNTY | 2007-12-13 | — | — | US | disclosed |
| WO-2005115338-A2 | MACROMOLECULAR GSH-ACTIVATED GLYOXYLASE I INHIBITORS | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (US) | 2005-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287672-A1 | Macromolecular Gsh-Activiated Glyoxylase I Inhibitors | GLO1, GGT1, GSTA1 | GSTP1 4/4885CYP2C19 1559/4885TP53 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.