SCHEMBL5496720

SCHEMBL5496720

CCCCCCCC/C=C\CCCCCCCC(=O)O[C@@H](CO)COCCCCCCCCCCCCCCCC

nearest known ligand 0.88

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 3/20 0.78
PRKCE Q02156 2/20 0.78
PRKCQ Q04759 2/20 0.78
PRKCD Q05655 2/20 0.78
MAPT P10636 2/20 0.67
FAAH O00519 1/20 0.67
ALDH1A1 P00352 1/20 0.67
HPGD P15428 1/20 0.67
CNR1 P21554 1/20 0.67
CNR2 P34972 1/20 0.67
S1PR1 P21453 1/20 0.67
MAPK1 P28482 1/20 0.63
DAGLA Q9Y4D2 1/20 0.60
DGKA P23743 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22558535 1.00 PRKCA (0.78) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL27973555 1.00 PRKCA (0.78) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL27611142 1.00 PRKCA (0.78) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL9754681 1.00 PRKCA (0.78) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL2520687 1.00 PRKCA (0.78) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL9754687 1.00 PRKCA (0.78) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL29767903 1.00 PRKCA (0.78) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL10491979 1.00 PRKCA (0.78) PRKCAPRKCEPRKCQPRKCDMAPT
Ether SCHEMBL10492083 0.96 PRKCA (0.73) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL10492005 0.96 ALDH1A1 (0.74) PRKCAPRKCEPRKCQPRKCDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109922808-A Liposome formulations for the treatment of cancer 法国施维雅药厂 2019-06-21 CN claimed
CN-105050614-B Stimulate the peptide with reduced toxicity of Cholesterol Efflux 加利福尼亚大学董事会 2019-04-05 CN claimed
CN-108291228-A C/EBP α SARNA compositions and methods of use 米纳治疗有限公司 2018-07-17 CN claimed
CN-114863996-A Method for rapidly evaluating neurotoxicity of bisphenol compound 华南师范大学 2022-08-05 CN disclosed
CN-105377316-B Method for preparing an object supporting a lipid bilayer 利宝涂料私人有限公司 2019-09-06 CN disclosed
CN-109922808-A Liposome formulations for the treatment of cancer 法国施维雅药厂 2019-06-21 CN disclosed
CN-109906075-A Liposomal corticosteroids for local injection in inflamed lesions or areas 恩瑟拉德斯医药有限公司 2019-06-18 CN disclosed
CN-109790212-A Cytosol penetrates antibody and application thereof 奥隆制药 2019-05-21 CN disclosed
CN-109310634-A Nanosiliposomes for sustained delivery of tacrolimus for treatment of anterior segment ocular diseases 南洋理工大学 2019-02-05 CN disclosed
CN-106852146-A Cell penetrating peptides and methods of making and using the same 塞克洛波特斯公司 2017-06-13 CN disclosed
CN-106470681-A Supramolecular assembly medicine 茵维特丝肿瘤学私营有限责任公司 2017-03-01 CN disclosed
CN-106456738-A Novel methods for inducing an immune response 葛兰素史密丝克莱恩生物有限公司 2017-02-22 CN disclosed
US-20070077283-A1 METHOD OF ENHANCING TRANSMUCOSAL DELIVERY OF THERAPEUTIC COMPOUNDS NASTECH PHARMACEUTICAL COMPANY INC. 2007-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070077283-A1 METHOD OF ENHANCING TRANSMUCOSAL DELIVERY OF THERAPEUTIC COMPOUNDS PGF, PLAT, PTAFR PRKCA 1613/4885PRKCE 2285/4885PRKCQ 1994/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.