Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.49 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 4/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26565876 | 0.78 | CA12 (0.51) | KDM4EALDH1A1MAPTHSD17B10GAA | |
| SCHEMBL21216702 | 0.77 | ALDH1A1 (0.60) | LNPEPKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL29691521 | 0.77 | ALDH1A1 (0.60) | LNPEPKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL2912873 | 0.76 | KDM4E (0.73) | KDM4EALDH1A1MAPTHSD17B10GAA | |
| SCHEMBL28831138 | 0.75 | NPC1 (0.51) | ALDH1A1MAPTHPGDCASP1TSHR | |
| SCHEMBL8420351 | 0.74 | ALDH1A1 (0.57) | ERAP2LNPEPKDM4EALDH1A1MAPT | |
| SCHEMBL2315127 | 0.74 | MAPT (0.64) | KDM4EALDH1A1MAPTHSD17B10GAA | |
| SCHEMBL1680679 | 0.74 | ALDH1A1 (0.64) | LNPEPKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL29615917 | 0.74 | ALDH1A1 (0.64) | LNPEPKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL3497730 | 0.74 | KDM4E (0.64) | KDM4EALDH1A1MAPTHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070004684-A1 | Alpha-Carbolines as CDK-1 inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004684-A1 | Alpha-Carbolines as CDK-1 inhibitors | CDKL1, CDK1, CCNA1 | ERAP2 4661/4885LNPEP 4656/4885KDM4E 521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.