Fluorene

Fluorene

SCHEMBL5496896

OBO.c1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.56
ALDH1A1 P00352 3/20 0.52
KDM4E B2RXH2 2/20 0.52
NPC1 O15118 2/20 0.52
MAPT P10636 2/20 0.52
RAB9A P51151 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
LMNA P02545 1/20 0.52
HPGD P15428 1/20 0.52
SRD5A2 P31213 1/20 0.50
CYP1A2 P05177 3/20 0.47
CYP3A4 P08684 2/20 0.47
BCHE P06276 1/20 0.46
CES1 P23141 1/20 0.46
HTR2C P28335 2/20 0.46
HTR2B P41595 2/20 0.46
DRD2 P14416 1/20 0.46
ADRA1D P25100 1/20 0.46
HTR2A P28223 1/20 0.46
HTR7 P34969 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorene SCHEMBL21837361 1.00 MAOA (0.56) MAOAALDH1A1KDM4ENPC1MAPT
Fluorene SCHEMBL545861 0.88 MAOA (0.68) MAOAALDH1A1KDM4ENPC1MAPT
Fluorene SCHEMBL31388525 0.88 MAOA (0.68) MAOAALDH1A1KDM4ENPC1MAPT
Fluorene SCHEMBL8180 0.88 MAOA (0.68) MAOAALDH1A1KDM4ENPC1MAPT
Fluorene SCHEMBL29355380 0.88 MAOA (0.68) MAOAALDH1A1KDM4ENPC1MAPT
Fluorene SCHEMBL29478468 0.88 MAOA (0.68) MAOAALDH1A1KDM4ENPC1MAPT
Fluorene SCHEMBL3139239 0.86 MAOA (0.59) MAOAALDH1A1KDM4ENPC1MAPT
Fluorene SCHEMBL21837362 0.85 MAOA (0.48) MAOAALDH1A1KDM4ENPC1MAPT
SCHEMBL1690447 0.85 CYP1A2 (0.50) MAOAALDH1A1MAPTCYP1A2CYP3A4
Fluorene SCHEMBL9791437 0.85 MAOA (0.65) MAOAALDH1A1KDM4ENPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504771-A Spiropyran derivative with color and fluorescence dual switch, photochromic material, and preparation method and application thereof 安徽省东超科技有限公司 2025-02-25 CN claimed
CN-118878402-A Preparation method of trifluoromethyl ketone compound based on palladium catalysis of C-N bond cleavage 大连理工大学 2024-11-01 CN claimed
CN-106700035-B A kind of star-like white light polymer of three arm of double-core and preparation method thereof 福建师范大学 2018-10-09 CN claimed
CN-104267578-B A kind of sulfosalt class photo-acid agent containing fluorenes, preparation method and applications 同济大学 2017-12-05 CN claimed
CN-106700035-A Dual-core three-arm star-type white light-emitting polymer and preparation method thereof 福建师范大学 2017-05-24 CN claimed
CN-104267578-A Fluorene-containing sulfonium salt photoacid generator (PAG) and its preparation method and use UNIV TONGJI 2015-01-07 CN claimed
EP-1425168-A4 LIGHT-EMITTING ORGANIC OLIGOMER COMPOSITIONS UNIV ROCHESTER (US) 2007-01-03 EP claimed
EP-1425168-A2 LIGHT-EMITTING ORGANIC OLIGOMER COMPOSITIONS University of Rochester (US) 2004-06-09 EP claimed
US-20030039838-A1 Light-emitting organic oligomer compositions UNIVERSITY OF ROCHESTER 2003-02-27 US claimed
WO-2003008475-A2 LIGHT-EMITTING ORGANIC OLIGOMER COMPOSITIONS UNIVERSITY OF ROCHESTER (US) 2003-01-30 WO claimed
CN-119504771-A Spiropyran derivative with color and fluorescence dual switch, photochromic material, and preparation method and application thereof 安徽省东超科技有限公司 2025-02-25 CN disclosed
CN-114560874-A Cationic water-soluble near-infrared two-zone fluorescence imaging contrast agent and application thereof 南京邮电大学 2022-05-31 CN disclosed
CN-106700035-B A kind of star-like white light polymer of three arm of double-core and preparation method thereof 福建师范大学 2018-10-09 CN disclosed
CN-106700035-A Dual-core three-arm star-type white light-emitting polymer and preparation method thereof 福建师范大学 2017-05-24 CN disclosed
EP-1425168-A4 LIGHT-EMITTING ORGANIC OLIGOMER COMPOSITIONS UNIV ROCHESTER (US) 2007-01-03 EP disclosed
US-7057009-B2 Crosslinking polyfluorene; molecular orientation UNIVERSITY OF ROCHESTER (US) 2006-06-06 US disclosed
EP-1425168-A2 LIGHT-EMITTING ORGANIC OLIGOMER COMPOSITIONS University of Rochester (US) 2004-06-09 EP disclosed
US-20030039838-A1 Light-emitting organic oligomer compositions UNIVERSITY OF ROCHESTER 2003-02-27 US disclosed
WO-2003008475-A2 LIGHT-EMITTING ORGANIC OLIGOMER COMPOSITIONS UNIVERSITY OF ROCHESTER (US) 2003-01-30 WO disclosed