Fluorene

Fluorene

SCHEMBL3139239

CO.c1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.59
ALDH1A1 P00352 5/20 0.54
NPC1 O15118 3/20 0.54
RAB9A P51151 3/20 0.54
KDM4E B2RXH2 1/20 0.54
LMNA P02545 1/20 0.54
MAPT P10636 1/20 0.54
HPGD P15428 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
SRD5A2 P31213 1/20 0.52
CYP1A2 P05177 3/20 0.50
ADRA2A P08913 2/20 0.50
SLC6A2 P23975 2/20 0.50
SLC6A4 P31645 2/20 0.50
HTR2C P28335 1/20 0.50
HTR2B P41595 1/20 0.50
CYP3A4 P08684 1/20 0.48
BCHE P06276 1/20 0.48
CES1 P23141 1/20 0.48
CHRM2 P08172 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorene SCHEMBL28150649 0.91 MAOA (0.62) MAOAALDH1A1NPC1RAB9AKDM4E
Fluorene SCHEMBL545861 0.91 MAOA (0.68) MAOAALDH1A1NPC1RAB9AKDM4E
Fluorene SCHEMBL29355380 0.91 MAOA (0.68) MAOAALDH1A1NPC1RAB9AKDM4E
Fluorene SCHEMBL31388525 0.91 MAOA (0.68) MAOAALDH1A1NPC1RAB9AKDM4E
Fluorene SCHEMBL8180 0.91 MAOA (0.68) MAOAALDH1A1NPC1RAB9AKDM4E
Fluorene SCHEMBL29478468 0.91 MAOA (0.68) MAOAALDH1A1NPC1RAB9AKDM4E
Fluorene SCHEMBL28946342 0.88 MAOA (0.59) MAOAALDH1A1NPC1RAB9AKDM4E
Fluorene SCHEMBL28872524 0.88 MAOA (0.59) MAOAALDH1A1NPC1RAB9AKDM4E
Fluorene SCHEMBL27865340 0.88 MAOA (0.59) MAOAALDH1A1NPC1RAB9AKDM4E
Fluorene SCHEMBL1080516 0.88 MAOA (0.65) MAOAALDH1A1NPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116554444-B Polymer for lithographic medium composition and lithographic medium composition 嘉庚创新实验室 2024-03-29 CN disclosed
CN-117122696-A Thrombus targeting self-sensitization hybridization nano-assembly, preparation method and application thereof 沈阳药科大学 2023-11-28 CN disclosed
CN-116554444-A Polymer for lithographic medium composition and lithographic medium composition 嘉庚创新实验室 2023-08-08 CN disclosed
CN-112724003-B Preparation method of 9-fluorenylformaldehyde 常州吉恩药业有限公司 2022-12-27 CN disclosed
CN-112724003-A Preparation method of 9-fluorenylformaldehyde 常州吉恩药业有限公司 2021-04-30 CN disclosed
CN-111825563-A Preparation method of beta-homoglutamic acid 中国科学院福建物质结构研究所 2020-10-27 CN disclosed
CN-104470971-B Energy ray curable resin composition and its solidfied material 日本化药株式会社 2018-06-22 CN disclosed
CN-105073800-B Energy ray-curable resin composition and cured product thereof 日本化药株式会社 2018-05-04 CN disclosed
CN-107556457-A Resin combination and its solidfied material 日本化药株式会社 2018-01-09 CN disclosed
CN-104813741-B Resin combination and its solidfied material (1) 日本化药株式会社 2018-01-05 CN disclosed
CN-104470971-A Energy ray-curable resin composition and cured product thereof NIPPON KAYAKU KK 2015-03-25 CN disclosed
CN-101375428-B Organic light emitting transistor element and method for manufacturing same DAINIPPON PRINTING CO LTD 2010-12-22 CN disclosed
CN-101336491-B Organic light emitting transistor device and method for manufacturing the same DAINIPPON PRINTING CO LTD 2010-12-08 CN disclosed
CN-101379881-B Organic light-emitting transistor device and method for manufacturing same DAINIPPON PRINTING CO LTD 2010-06-09 CN disclosed
US-7687618-B2 reaction of an oligonucleotide having a labile protecting group bound to a terminal hydroxy group, and a labeling compound; nucleophilic substitution reaction; lower reaction times and yields are advantageous for the user because they permit a high throughput with low technical requirements NIMBLEGEN SYSTEMS GMBH (DE) 2010-03-30 US disclosed
CN-101379881-A Organic light-emitting transistor device and method for manufacturing same DAINIPPON PRINTING CO LTD (JP) 2009-03-04 CN disclosed
CN-101375428-A Organic light emitting transistor element and method for manufacturing same DAINIPPON PRINTING CO LTD (JP) 2009-02-25 CN disclosed
CN-101336491-A Organic light emitting transistor device and method for manufacturing the same DAINIPPON PRINTING CO LTD (JP) 2008-12-31 CN disclosed
US-20060122382-A1 Method of manufacturing labelled oligonucleotide conjugates NIMBLEGENSYSTEMS GMBH (DE) 2006-06-08 US disclosed
WO-2004035600-A1 METHOD OF MANUFACTURING LABELLED OLIGONUCLEOTIDE CONJUGATES CHEMOGENIX GMBH (DE) 2004-04-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122382-A1 Method of manufacturing labelled oligonucleotide conjugates DUT, RNGTT, OSGEP MAOA 833/4885ALDH1A1 326/4885NPC1 1595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.