Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL27917454 | 0.95 | THRB (0.36) | THRBLMNASHBG | |
| SCHEMBL16287489 | 0.89 | SHBG (0.44) | THRBLMNASHBG | |
| SCHEMBL16287469 | 0.87 | SHBG (0.48) | THRBLMNASHBG | |
| SCHEMBL14743720 | 0.87 | SHBG (0.48) | THRBLMNASHBG | |
| SCHEMBL11842539 | 0.87 | SHBG (0.48) | THRBLMNASHBG | |
| SCHEMBL28088063 | 0.87 | SHBG (0.48) | THRBLMNASHBG | |
| SCHEMBL7301138 | 0.83 | SLC6A2 (0.36) | THRBLMNA | |
| SCHEMBL196146 | 0.81 | THRB (0.31) | THRB | |
| SCHEMBL2754804 | 0.77 | — | — | |
| SCHEMBL8760918 | 0.76 | THRB (0.35) | THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690862-A1 | NOVEL QUINOLONE DERIVATIVES AND PROCESSES FOR PREPARING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1996-01-10 | — | — | EP | claimed |
| WO-1994015938-A1 | NOVEL QUINOLONE DERIVATIVES AND PROCESSES FOR PREPARING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1994-07-21 | — | — | WO | claimed |
| US-20130066060-A1 | Gene for Identifying Individuals with Familial Dysautonomia | THE GENERAL HOSPITAL CORPORATION (US) | 2013-03-14 | — | — | US | disclosed |
| CN-101544581-B | Processes for preparation of bicyclic compounds and intermediates therefor | DAIICHI SEIYAKU CO | 2013-02-06 | — | — | CN | disclosed |
| CN-101544581-A | Processes for preparation of bicyclic compounds and intermediates therefor | DAIICHI SEIYAKU CO (JP) | 2009-09-30 | — | — | CN | disclosed |
| US-20090176222-A1 | Gene for Identifying Individuals with Familial Dysautonomia | THE GENERAL HOSPITAL CORPORATION (US) | 2009-07-09 | — | — | US | disclosed |
| CN-100473645-C | Processes for preparation of bicyclic compounds and intermediates therefor | DAIICHI SEIYAKU CO (JP) | 2009-04-01 | — | — | CN | disclosed |
| EP-1310487-B1 | PROCESSES FOR PREPARATION OF BICYCLIC COMPOUNDS AND INTERMEDIATES THEREFOR | DAIICHI SEIYAKU CO (JP) | 2007-01-03 | — | — | EP | disclosed |
| CN-1293054-C | Process and intermediates for preparation of bicyclic compounds | DAIICHI SEIYAKU CO (JP) | 2007-01-03 | — | — | CN | disclosed |
| US-7074837-B2 | Processes for preparation of bicyclic compounds and intermediates therefor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-07-11 | — | — | US | disclosed |
| US-20050272797-A1 | Processes for preparation of bicyclic compounds and intermediates therefor | DAIICHI PHARMACEUTICAL CO., LTD. | 2005-12-08 | — | — | US | disclosed |
| CN-1680294-A | Processes for preparation of bicyclic compounds and intermediates therefor | DAIICHI SEIYAKU CO (JP) | 2005-10-12 | — | — | CN | disclosed |
| US-20040019223-A1 | Processes for preparation of bicyclic compounds and intermediates therefor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-01-29 | — | — | US | disclosed |
| CN-1468218-A | Process for preparation of bicyclic compounds and intermediates therefor | ��һ��������ҩ��ʽ���� | 2004-01-14 | — | — | CN | disclosed |
| EP-1310487-A1 | PROCESSES FOR PREPARATION OF BICYCLIC COMPOUNDS AND INTERMEDIATES THEREFOR | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-05-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019223-A1 | Processes for preparation of bicyclic compounds and intermediates therefor | DCXR, CYP51A1, WEE1 | THRB 4320/4885LMNA 1331/4885SHBG 4571/4885 |
| US-20050272797-A1 | Processes for preparation of bicyclic compounds and intermediates therefor | DCXR, WEE1, CYP51A1 | THRB 4304/4885LMNA 1326/4885SHBG 4557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.