Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 4/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27496685 | 0.84 | THRB (0.35) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL3959088 | 0.80 | THRB (0.36) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL17727598 | 0.79 | TSHR (0.41) | TSHRHPGDTHRBALDH1A1 | |
| SCHEMBL105694 | 0.70 | TSHR (0.55) | TSHRHPGDTHRBATMALDH1A1 | |
| SCHEMBL19583231 | 0.69 | TSHR (0.58) | TSHRHPGDTHRBATMALDH1A1 | |
| SCHEMBL5369950 | 0.69 | TSHR (0.53) | TSHRHPGDTHRBATMALDH1A1 | |
| SCHEMBL752302 | 0.69 | TSHR (0.53) | TSHRHPGDTHRBATMALDH1A1 | |
| SCHEMBL5251142 | 0.69 | TSHR (0.45) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL51558 | 0.68 | TSHR (0.56) | TSHRHPGDTHRBATMALDH1A1 | |
| SCHEMBL3422881 | 0.68 | TSHR (0.56) | TSHRHPGDTHRBATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205362-B2 | Method for controlled radical polymerization | bioMérieux (FR) | 2007-04-17 | — | — | US | disclosed |