Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557087 | 0.88 | SIGMAR1 (0.42) | SIGMAR1IDO1NQO2CYP3A4NPSR1 | |
| SCHEMBL6557081 | 0.87 | NPSR1 (0.43) | SIGMAR1IDO1CYP3A4NPSR1BCHE | |
| SCHEMBL6385864 | 0.84 | BCHE (0.40) | SIGMAR1IDO1NQO2CYP3A4NPSR1 | |
| SCHEMBL6387372 | 0.79 | CKS1B (0.42) | SIGMAR1IDO1CA1CA2CYP3A4 | |
| SCHEMBL6559029 | 0.76 | SIGMAR1 (0.37) | SIGMAR1IDO1BCHECKS1BSKP1 | |
| SCHEMBL5497821 | 0.75 | SIGMAR1 (0.38) | SIGMAR1IDO1CA1CA2CYP3A4 | |
| SCHEMBL25048413 | 0.74 | CA1 (0.60) | SIGMAR1IDO1CA1CA2KDM4E | |
| SCHEMBL6385861 | 0.71 | BCHE (0.40) | SIGMAR1IDO1NQO2NPSR1BCHE | |
| SCHEMBL31505697 | 0.69 | MALT1 (0.51) | SIGMAR1IDO1CA1CA2NQO2 | |
| SCHEMBL5497926 | 0.69 | TLR7 (0.38) | SIGMAR1IDO1CA1CA2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556389-B1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2007-07-25 | — | — | EP | disclosed |