Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 2/20 | 0.35 |
| ▸ | SKP1 | P63208 | 2/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 3/20 | 0.35 |
| ▸ | ACACA | Q13085 | 3/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557087 | 0.79 | SIGMAR1 (0.42) | SIGMAR1BCHECKS1BSKP1SKP2 | |
| SCHEMBL6557081 | 0.78 | NPSR1 (0.43) | SIGMAR1BCHECKS1BSKP1SKP2 | |
| SCHEMBL6385864 | 0.77 | BCHE (0.40) | SIGMAR1BCHECKS1BSKP1SKP2 | |
| SCHEMBL5497823 | 0.76 | SIGMAR1 (0.43) | SIGMAR1BCHECKS1BSKP1SKP2 | |
| SCHEMBL630419 | 0.75 | IDO1 (0.47) | SIGMAR1IDO1KDM4ASYK | |
| SCHEMBL6559439 | 0.75 | TSHR (0.40) | SIGMAR1BCHE | |
| SCHEMBL6387372 | 0.74 | CKS1B (0.42) | SIGMAR1BCHECKS1BSKP1SKP2 | |
| SCHEMBL6557082 | 0.72 | PRMT5 (0.40) | BCHECKS1BSKP1SKP2IDO1 | |
| SCHEMBL6557080 | 0.70 | AGTR1 (0.39) | SIGMAR1BCHEKDM4ASYKCYP1A2 | |
| SCHEMBL6559033 | 0.70 | KDM4E (0.40) | BCHEKDM4ASYKCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392704-A1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002090364-A1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |