Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.42 |
| ▸ | SKP1 | P63208 | 2/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | AKT1 | P31749 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557087 | 0.82 | SIGMAR1 (0.42) | CKS1BSKP1SKP2SIGMAR1BCHE | |
| SCHEMBL6557081 | 0.81 | NPSR1 (0.43) | CKS1BSKP1SKP2SIGMAR1BCHE | |
| SCHEMBL6385864 | 0.80 | BCHE (0.40) | CKS1BSKP1SKP2SIGMAR1BCHE | |
| SCHEMBL5497823 | 0.79 | SIGMAR1 (0.43) | CKS1BSKP1SKP2SIGMAR1BCHE | |
| SCHEMBL6387369 | 0.75 | CKS1B (0.39) | CKS1BSKP1SKP2SIGMAR1BCHE | |
| SCHEMBL6559029 | 0.74 | SIGMAR1 (0.37) | CKS1BSKP1SKP2SIGMAR1BCHE | |
| SCHEMBL5492726 | 0.70 | CKS1B (0.41) | CKS1BSKP1SKP2SIGMAR1BCHE | |
| SCHEMBL22833183 | 0.67 | CTSL (0.54) | CKS1BSKP1SKP2SIGMAR1IDO1 | |
| SCHEMBL6385861 | 0.67 | BCHE (0.40) | CKS1BSKP1SKP2SIGMAR1BCHE | |
| SCHEMBL31505697 | 0.67 | MALT1 (0.51) | CKS1BSKP1SKP2SIGMAR1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556389-A1 | CEPHEM COMPOUNDS | Astellas Pharma Inc. (JP) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004039814-A1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2004-05-13 | — | — | WO | disclosed |