Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL400749 | 0.78 | TSHR (0.54) | TSHRALDH1A1AOC3MAPK1KDM4E | |
| Hydrochloric Acid SCHEMBL7899272 | 0.76 | TSHR (0.52) | TSHRALDH1A1AOC3MAPK1KDM4E | |
| SCHEMBL8626770 | 0.74 | ALDH1A1 (0.42) | TSHRALDH1A1AOC3NPSR1LMNA | |
| SCHEMBL7278001 | 0.72 | TAAR1 (0.50) | AOC3SLC6A2SLC6A4ADRA1ASLC6A3 | |
| SCHEMBL79749 | 0.71 | ALDH1A1 (0.43) | TSHRALDH1A1AOC3MGLLG6PC1 | |
| SCHEMBL6644202 | 0.70 | TSHR (0.50) | TSHRALDH1A1AOC3MGLLMAPK1 | |
| SCHEMBL3029785 | 0.70 | TSHR (0.50) | TSHRALDH1A1AOC3MGLLMAPK1 | |
| SCHEMBL5095070 | 0.69 | KCNH2 (0.44) | TSHRALDH1A1MAPK1KCNH2LMNA | |
| Hydrochloric Acid SCHEMBL28690523 | 0.69 | ALDH1A1 (0.42) | TSHRALDH1A1AOC3MGLLG6PC1 | |
| SCHEMBL10660626 | 0.69 | TSHR (0.54) | TSHRALDH1A1AOC3MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786792-A2 | THIAZOLE DERIVATIVES HAVING VAP-1 INHIBITORY ACTIVITY | Astellas Pharma Inc. (JP) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006011631-A2 | THIAZOLE DERIVATIVES HAVING VAP-1 INHIBITORY ACTIVITY | ASTELLAS PHARMA INC. (JP) | 2006-02-02 | — | — | WO | disclosed |