Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11688180 | 0.77 | APLNR (0.56) | ALDH1A1CA2APLNRTSHRNR3C1 | |
| SCHEMBL5498059 | 0.74 | TSHR (0.46) | ALDH1A1TSHRAOC3LMNANPSR1 | |
| SCHEMBL10312253 | 0.70 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2POLBCA2APLNR | |
| SCHEMBL2492170 | 0.70 | TSHR (0.53) | ALDH1A1SMN1; SMN2POLBCA2TSHR | |
| SCHEMBL2057187 | 0.69 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2POLBCA2TSHR | |
| SCHEMBL28480609 | 0.68 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2POLBCA2TSHR | |
| SCHEMBL24571678 | 0.66 | TSHR (0.68) | ALDH1A1SMN1; SMN2POLBCA2TSHR | |
| SCHEMBL12808838 | 0.66 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2POLBTSHRPTPN1 | |
| SCHEMBL2103432 | 0.66 | SMN1; SMN2 (0.58) | ALDH1A1SMN1; SMN2POLBCA2APLNR | |
| SCHEMBL11763516 | 0.65 | CA1 (0.39) | ALDH1A1SMN1; SMN2POLBCA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846119-A1 | THIENOPYRIMIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-06-10 | — | — | EP | disclosed |
| WO-1997007119-A1 | THIENOPYRIMIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-02-27 | — | — | WO | disclosed |